Consolidated Statements of Cash Flows - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2017	Mar. 31, 2016
Cash flows from operating activities
Net loss	$ (15,223)	$ (13,599)
Adjustments to reconcile net loss to net cash used in operating activities:
Non-cash other expense, net	(266)	(924)
Non-cash interest income	(30)	(44)
Depreciation and amortisation expense	76	45
Stock-based compensation	684	580
Deferred income taxes	178	(18)
Other, net	86	1
Changes in operating assets and liabilities:
Changes in long-term receivables	(5)	(15)
Changes in other receivables	(1,586)	(1,638)
Changes in accounts payable	1,789	2,235
Changes in accrued expenses and other liabilities	(383)	2,491
Changes in other non-current liabilities	6	8
Changes in income tax liabilities	(10)	(1)
Net cash used in operating activities	(14,684)	(10,879)
Cash flows from investing activities
Purchases of plant and equipment and intangible assets	(25)	(67)
Proceeds from sales of property, plant and equipment	2
Proceeds from sales of available-for-sale securities	10,000	3,000
Net cash provided by investing activities	9,977	2,933
Cash flows from financing activities
Proceeds from long-term borrowings	229
Proceeds from exercise of stock options	10	29
Equity transaction costs	(1,410)
Net cash provided by (used in) financing activities	(1,171)	29
Effects of foreign currency translation on cash and cash equivalents	266	924
Net decrease in cash and cash equivalents	(5,612)	(6,993)
Cash and cash equivalents at beginning of period	32,778	36,446
Cash and cash equivalents at end of period	$ 27,166	$ 29,453