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Sinovant License Agreement (Details)
$ in Thousands
1 Months Ended 3 Months Ended 12 Months Ended
Feb. 28, 2019
USD ($)
Mar. 31, 2018
USD ($)
Dec. 31, 2018
USD ($)
item
Sep. 30, 2018
USD ($)
Jun. 30, 2018
USD ($)
Mar. 31, 2018
USD ($)
Dec. 31, 2017
USD ($)
Sep. 30, 2017
USD ($)
Jun. 30, 2017
USD ($)
Mar. 31, 2017
USD ($)
Dec. 31, 2018
USD ($)
item
Dec. 31, 2017
USD ($)
Dec. 31, 2016
USD ($)
License Agreement                          
Revenues     $ 797 $ 461 $ 847 $ 7,551 $ 1,122 $ 1,468 $ 1,051 $ 1,678 $ 9,656 $ 5,319 $ 6,482
Sinovant Sciences, LTD | License Agreement                          
License Agreement                          
Notice period for termination of agreement                     180 days    
Number of deliverables | item     2               2    
Sinovant Sciences, LTD | License Agreement | Achievement of certain regulatory and commercial milestones                          
License Agreement                          
Maximum contingent milestone payment     $ 91,500               $ 91,500    
Sinovant Sciences, LTD | License Agreement | Subsequent regulatory approval                          
License Agreement                          
Maximum contingent milestone payment     $ 4,000               $ 4,000    
Sinovant Sciences, LTD | License Agreement | Clinical trial application submission                          
License Agreement                          
Milestone payment received $ 1,500                        
Collaboration revenue - Upfront payment | Sinovant Sciences, LTD | License Agreement                          
License Agreement                          
Revenues   $ 5,000