Number of vesting periods

No definition available.

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- Definition

Represents the automatic annual increase in shares reserved and available for issuance in number of shares. The automatic increases occur on the first day of the year beginning in the fiscal year ending December 2018.

+ References

No definition available.

+ Details

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- Definition

Represents the automatic annual increase in shares reserved and available for issuance as a percentage to outstanding number of shares. The automatic increases occur on the first day of the year beginning in the fiscal year ending December 2018.

+ References

No definition available.

+ Details

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- Definition

Period from grant date that an equity-based award expires if the drug is not approved, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

No definition available.

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- Definition

Period of time between issuance and maturity of bond, in PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

No definition available.

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- Definition

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition

Weighted average period over which unrecognized compensation is expected to be recognized for equity-based compensation plans, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

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- Definition

Unrecognized cost of unvested options awarded to employees as compensation.

+ References

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- Definition

Period which an employee's right to exercise an award is no longer contingent on satisfaction of either a service condition, market condition or a performance condition, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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- Definition

The number of grants made during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

+ References

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- Definition

The weighted average fair value at grant date for nonvested equity-based awards issued during the period on other than stock (or unit) option plans (for example, phantom stock or unit plan, stock or unit appreciation rights plan, performance target plan).

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- Definition

The number of non-vested equity-based payment instruments, excluding stock (or unit) options, that validly exist and are outstanding as of the balance sheet date.

+ References

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- Definition

A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.

+ References

No definition available.

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- References

No definition available.

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- Definition

The estimated dividend rate (a percentage of the share price) to be paid (expected dividends) to holders of the underlying shares over the option's term.

+ References

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- Definition

The estimated measure of the percentage by which a share price is expected to fluctuate during a period. Volatility also may be defined as a probability-weighted measure of the dispersion of returns about the mean. The volatility of a share price is the standard deviation of the continuously compounded rates of return on the share over a specified period. That is the same as the standard deviation of the differences in the natural logarithms of the stock prices plus dividends, if any, over the period.

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- Definition

The risk-free interest rate assumption that is used in valuing an option on its own shares.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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- Definition

Number of additional shares authorized for issuance under an established share-based compensation plan.

+ References

No definition available.

+ Details

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- Definition

The maximum number of shares (or other type of equity) originally approved (usually by shareholders and board of directors), net of any subsequent amendments and adjustments, for awards under the equity-based compensation plan. As stock or unit options and equity instruments other than options are awarded to participants, the shares or units remain authorized and become reserved for issuance under outstanding awards (not necessarily vested).

+ References

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- Definition

The difference between the maximum number of shares (or other type of equity) authorized for issuance under the plan (including the effects of amendments and adjustments), and the sum of: 1) the number of shares (or other type of equity) already issued upon exercise of options or other equity-based awards under the plan; and 2) shares (or other type of equity) reserved for issuance on granting of outstanding awards, net of cancellations and forfeitures, if applicable.

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- References

No definition available.

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- Definition

The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.

+ References

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- Definition

The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan.

+ References

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- Definition

The number of shares under options that were cancelled during the reporting period as a result of occurrence of a terminating event specified in contractual agreements pertaining to the stock option plan.

+ References

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- Definition

Gross number of share options (or share units) granted during the period.

+ References

No definition available.

+ Details

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- Definition

The weighted average grant-date fair value of options granted during the reporting period as calculated by applying the disclosed option pricing methodology.

+ References

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- Definition

Number of options outstanding, including both vested and non-vested options.

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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- Definition

A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.

+ References

No definition available.

+ Details

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- Definition

Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.

+ References

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- References

No definition available.

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- Definition

Weighted average price at which grantees could have acquired the underlying shares with respect to stock options that were terminated.

+ References

No definition available.

+ Details

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- Definition

Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.

+ References

No definition available.

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- Definition

The floor of a customized range of exercise prices for purposes of disclosing shares potentially issuable under outstanding stock option awards on all stock option plans and other required information pertaining to awards in the customized range.

+ References

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- Definition

The number of shares reserved for issuance pertaining to the outstanding stock options as of the balance sheet date for all option plans in the customized range of exercise prices.

+ References

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- Definition

The ceiling of a customized range of exercise prices for purposes of disclosing shares potentially issuable under outstanding stock option awards on all stock option plans and other required information pertaining to awards in the customized range.

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- Definition

Percentage of vesting of share-based compensation awards.

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- Definition

Period from grant date that an equity-based award expires, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

+ References

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- Definition

Expected term of share-based compensation awards, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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- Definition

Weighted average remaining contractual term of exercisable stock options, in 'PnYnMnDTnHnMnS' format, for example, 'P1Y5M13D' represents the reported fact of one year, five months, and thirteen days.

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- Definition

Number of share options (or share units) exercised during the current period.

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Share-Based Payments - 2017 Share Incentive Plan (Details) $ / shares in Units, $ in Thousands		12 Months Ended
	Jul. 26, 2017 shares	Dec. 31, 2018 USD ($) item $ / shares shares	Dec. 31, 2017 USD ($) $ / shares shares	Dec. 31, 2016 USD ($) $ / shares shares
Additional disclosures
Share-based compensation expense \| $		$ 5,154	$ 5,732	$ 2,545
2017 Share Incentive Plan
Weighted average exercise price in $ per share
Outstanding balance at beginning of year (in dollars per share) \| $ / shares		$ 6.92	$ 0.00
Granted (in dollars per share) \| $ / shares		5.27	6.92
Forfeited (in dollars per share) \| $ / shares		6.75
Outstanding balance at end of year (in dollars per share) \| $ / shares		5.41	$ 6.92	$ 0.00
Vested and exercisable balance at end of year (in dollars per share) \| $ / shares		$ 6.88
Options
Outstanding at beginning of year (in shares)		294,100	0
Granted (in shares)		2,199,225	294,100
Exercised (in shares)		0	0
Forfeited (in shares)		(94,900)
Outstanding at end of year (in shares)		2,398,425	294,100	0
Vested and exercisable at end of year (in shares)		119,287
2017 Share Incentive Plan \| $1.46 per share to $8.35 per share
Additional disclosures
Options outstanding (in shares)		2,398,425
Exercise price minimum range \| $ / shares		$ 1.46
Exercise price maximum range \| $ / shares		$ 8.35
Weighted average remaining contractual life		9 years 3 months 18 days
2017 Share Incentive Plan \| Ordinary Shares
Share-Based Payments
Number of shares authorized	3,000,000
Additional shares authorized	3,438,990
Shares available for grant		5,064,378
2017 Share Incentive Plan \| Ordinary Shares \| Minimum
Share-Based Payments
Annual increase, to be added on the first day of each fiscal year (in shares)	2,000,000
Annual increase, to be added on the first day of each fiscal year (as a percent)	4.00%
2017 Share Incentive Plan \| Stock Options
Share-Based Payments
Exercise period		10 years
Fair Value Assumptions
Expected term of options (in years)		6 years 1 month 6 days	6 years
Dividend yield (as a percent)		0.00%	0.00%
Additional disclosures
Share-based compensation expense \| $		$ 1,800	$ 100
Weighted-average grant date fair value (in dollars per share) \| $ / shares		$ 3.06	$ 3.98
Total unrecognized compensation related to unvested options \| $		$ 5,700
Recognition period		3 years 1 month 6 days
2017 Share Incentive Plan \| Stock Options \| Minimum
Fair Value Assumptions
Expected volatility (as a percent)		59.80%	59.50%
Risk-free interest rate (as a percent)		2.55%	1.93%
Additional disclosures
Term of U.S. treasury securities used to estimate risk free interest rate		5 years
2017 Share Incentive Plan \| Stock Options \| Maximum
Fair Value Assumptions
Expected volatility (as a percent)		61.40%	63.00%
Risk-free interest rate (as a percent)		3.03%	2.27%
Additional disclosures
Term of U.S. treasury securities used to estimate risk free interest rate		7 years
2017 Share Incentive Plan \| SARs
Share-Based Payments
Exercise period		10 years
2017 Share Incentive Plan \| Restricted Stock Units ("RSUs")
Additional disclosures
Share-based compensation expense \| $		$ 0
Restricted Stock Units
Restricted stock granted during the period		407,150
Weighted average grant date fair value per share \| $ / shares		$ 5.82
Number of shares outstanding		387,800
Expiration period if drug is not approved		2 years
2017 Share Incentive Plan \| Restricted Stock Units ("RSUs") \| Employees
Additional disclosures
Share-based compensation expense \| $		$ 200
Restricted Stock Units
Restricted stock granted during the period		834,300
Weighted average grant date fair value per share \| $ / shares		$ 2.16
Number of shares outstanding		834,300
Number of vesting periods \| item		3
Vesting period		6 months
2017 Share Incentive Plan \| Restricted Stock Units ("RSUs") \| Immediate vesting upon regulatory approval
Restricted Stock Units
Percentage that vests during the period		50.00%
2017 Share Incentive Plan \| Restricted Stock Units ("RSUs") \| Vesting upon the one-year-anniversary of FDA approval
Restricted Stock Units
Percentage that vests during the period		50.00%
Vesting period		1 year