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Commitments and Contingencies - Additional Information (Detail) - USD ($)
Sep. 30, 2021
Feb. 28, 2007
Developmental and Regulatory Milestone Payment [Member] | Novo License Agreement [Member] | Maximum [Member] | Other Indication [Member]    
Commitments And Contingencies [Line Items]    
Potential milestone payment   $ 115,000,000.0
Developmental and Regulatory Milestone Payment [Member] | Novo License Agreement [Member] | Maximum [Member] | Type 1 Diabetes [Member]    
Commitments And Contingencies [Line Items]    
Potential milestone payment   9,000,000.0
Developmental and Regulatory Milestone Payment [Member] | Novo License Agreement [Member] | Maximum [Member] | Type 2 Diabetes [Member]    
Commitments And Contingencies [Line Items]    
Potential milestone payment   50,500,000
Sales-based Milestones Payment [Member] | Novo License Agreement [Member]    
Commitments And Contingencies [Line Items]    
Potential milestone payment   $ 75,000,000.0
Phase 2 MRCT [Member] | Collaborative Arrangements [Member]    
Commitments And Contingencies [Line Items]    
Maximum contribution amount to clinical trial $ 3,000,000.0