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Accrued and Other Current Liabilities (Details) - USD ($)
$ in Thousands
Mar. 31, 2019
Dec. 31, 2018
Accrued Liabilities And Other Liabilities [Abstract]    
Accrued compensation $ 1,038 $ 2,643
Accrued contracted research and development costs 6,656 5,993
Accrued professional and consulting fees 447 807
Other 125 133
Total accrued and other current liabilities $ 8,266 $ 9,576