The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABBVIE INC Common 00287Y109 721,672 11,656,800 SH   SOLE   11,394,500 0 262,300
ALKERMES PLC SHS G01767105 325,686 7,535,533 SH   SOLE   7,353,733 0 181,800
NORTHWEST BIOTHERAPEUTICS INC Common 66737P600 15,065 25,915,937 SH   SOLE   24,815,028 0 1,100,909
PROTHENA CORP PLC SHS G72800108 360,254 10,304,751 SH   SOLE   9,934,090 0 370,661
REYNOLDS AMERICAN INC Common 761713106 502,760 9,322,463 SH   SOLE   9,072,345 0 250,118
THERAVANCE BIOPHARMA INC Common G8807B106 198,166 8,733,637 SH   SOLE   8,346,146 0 387,491
BIOGEN INC Common 09062X103 4,836 20,000 SH   SOLE   20,000 0 0