<SEC-DOCUMENT>0001193125-21-291044-index.html : 20211004
<SEC-HEADER>0001193125-21-291044.hdr.sgml : 20211004
<ACCEPTANCE-DATETIME>20211004165844
ACCESSION NUMBER:		0001193125-21-291044
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		10
FILED AS OF DATE:		20211004
DATE AS OF CHANGE:		20211004

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Metacrine, Inc.
		CENTRAL INDEX KEY:			0001634379
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				472297384
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-260023
		FILM NUMBER:		211303662

	BUSINESS ADDRESS:	
		STREET 1:		3985 SORRENTO VALLEY BLVD., SUITE C
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		858-369-7800

	MAIL ADDRESS:	
		STREET 1:		3985 SORRENTO VALLEY BLVD., SUITE C
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>d236019ds3.htm
<DESCRIPTION>S-3
<TEXT>
Document 1 - file: d236019ds3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-1.2
<SEQUENCE>2
<FILENAME>d236019dex12.htm
<DESCRIPTION>EX-1.2
<TEXT>
Document 2 - file: d236019dex12.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.6
<SEQUENCE>3
<FILENAME>d236019dex46.htm
<DESCRIPTION>EX-4.6
<TEXT>
Document 3 - file: d236019dex46.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.9
<SEQUENCE>4
<FILENAME>d236019dex49.htm
<DESCRIPTION>EX-4.9
<TEXT>
Document 4 - file: d236019dex49.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.10
<SEQUENCE>5
<FILENAME>d236019dex410.htm
<DESCRIPTION>EX-4.10
<TEXT>
Document 5 - file: d236019dex410.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.11
<SEQUENCE>6
<FILENAME>d236019dex411.htm
<DESCRIPTION>EX-4.11
<TEXT>
Document 6 - file: d236019dex411.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>7
<FILENAME>d236019dex51.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 7 - file: d236019dex51.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>8
<FILENAME>d236019dex231.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 8 - file: d236019dex231.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>9
<FILENAME>g236019dsp13.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 9 - file: g236019dsp13.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>10
<FILENAME>g236019g35s74.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 10 - file: g236019g35s74.jpg

</DOCUMENT>
</SEC-DOCUMENT>