<SEC-DOCUMENT>0001193125-20-252389-index.html : 20200923
<SEC-HEADER>0001193125-20-252389.hdr.sgml : 20200923
<ACCEPTANCE-DATETIME>20200923165902
ACCESSION NUMBER:		0001193125-20-252389
CONFORMED SUBMISSION TYPE:	S-8
PUBLIC DOCUMENT COUNT:		6
FILED AS OF DATE:		20200923
DATE AS OF CHANGE:		20200923
EFFECTIVENESS DATE:		20200923

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Metacrine, Inc.
		CENTRAL INDEX KEY:			0001634379
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				472297384
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-8
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-248996
		FILM NUMBER:		201192573

	BUSINESS ADDRESS:	
		STREET 1:		3985 SORRENTO VALLEY BLVD., SUITE C
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
		BUSINESS PHONE:		858-369-7800

	MAIL ADDRESS:	
		STREET 1:		3985 SORRENTO VALLEY BLVD., SUITE C
		CITY:			SAN DIEGO
		STATE:			CA
		ZIP:			92121
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-8
<SEQUENCE>1
<FILENAME>d27032ds8.htm
<DESCRIPTION>S-8
<TEXT>
Document 1 - file: d27032ds8.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>d27032dex51.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 2 - file: d27032dex51.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>d27032dex231.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 3 - file: d27032dex231.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.2
<SEQUENCE>4
<FILENAME>d27032dex992.htm
<DESCRIPTION>EX-99.2
<TEXT>
Document 4 - file: d27032dex992.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.3
<SEQUENCE>5
<FILENAME>d27032dex993.htm
<DESCRIPTION>EX-99.3
<TEXT>
Document 5 - file: d27032dex993.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>g27032g0923141612279.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: g27032g0923141612279.jpg

</DOCUMENT>
</SEC-DOCUMENT>