The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
Agenus Inc COM 00847G705   1,808,000 1,600,000 SH Call SOLE   1,600,000 0 0
Agenus Inc COM 00847G705   15,102,165 13,364,748 SH   SOLE   13,364,748 0 0
Alkermes PLC SHS G01767105   15,054,367 537,464 SH   SOLE   537,464 0 0
AstraZeneca PLC SPONSORED ADR 046353108   92,291,254 1,362,836 SH   SOLE   1,362,836 0 0
Axsome Therapeutics Inc COM 05464T104   5,616,920 80,368 SH   SOLE   80,368 0 0
Celldex Therapeutics Inc COM 15117B202   11,675,608 424,259 SH   SOLE   424,259 0 0
Celldex Therapeutics Inc COM 15117B202   5,504,000 200,000 SH Put SOLE   200,000 0 0
CRISPR Therapeutics AG NAMEN AKT H17182108   9,078,000 200,000 SH Put SOLE   200,000 0 0
CymaBay Therapeutics Inc COM 23257D103   164,606 11,040 SH Put SOLE   11,040 0 0
Cytokinetics Inc COM 23282W605   31,232,431 1,060,164 SH   SOLE   1,060,164 0 0
Cytokinetics Inc COM 23282W605   14,730,000 500,000 SH Put SOLE   500,000 0 0
Dexcom Inc COM 252131107   51,333,380 550,197 SH   SOLE   550,197 0 0
Dyne Therapeutics Inc COM 26818M108   6,138,792 685,133 SH   SOLE   685,133 0 0
Elanco Animal Health Inc COM 28414H103   40,576,670 3,610,024 SH   SOLE   3,610,024 0 0
Exelixis Inc COM 30161Q104   19,066,310 872,600 SH Put SOLE   872,600 0 0
Exelixis Inc COM 30161Q104   18,152,193 830,764 SH   SOLE   830,764 0 0
Exelixis Inc COM 30161Q104   874,000 40,000 SH Put SOLE   40,000 0 0
Geron Corp COM 374163103   7,849,398 3,702,546 SH   SOLE   3,702,546 0 0
IDEAYA Biosciences Inc COM 45166A102   27,983,305 1,037,187 SH   SOLE   1,037,187 0 0
IDEXX Laboratories Inc COM 45168D104   34,055,025 77,881 SH   SOLE   77,881 0 0
Immatics NV *W EXP 07/01/2025 N44445117   1,128,892 318,896 SH   SOLE   318,896 0 0
Immatics NV SHS N44445109   37,652,474 3,251,509 SH   SOLE   3,251,509 0 0
ImmunoGen Inc COM 45253H101   32,457,356 2,045,202 SH   SOLE   2,045,202 0 0
Immunovant Inc COM 45258J102   5,370,185 139,885 SH   SOLE   139,885 0 0
Inhibrx Inc COM 45720L107   13,639,445 743,294 SH   SOLE   743,294 0 0
Intuitive Surgical Inc COM 46120E602   50,647,134 173,277 SH   SOLE   173,277 0 0
Invesco QQQ TR UNIT SER 1 46090E953   17,913,500 50,000 SH   SOLE   50,000 0 0
IShares TR RUSSELL 2000 ETF 464287655   39,766,500 225,000 SH Put SOLE   225,000 0 0
Karuna Therapeutics Inc COM 48576A100   115,488 683 SH   SOLE   683 0 0
Kenvue Inc COM 49177J102   36,185,847 1,802,084 SH   SOLE   1,802,084 0 0
Marinus Pharmaceuticals Inc COM 56854Q200   2,580,830 320,600 SH Call SOLE   320,600 0 0
Marinus Pharmaceuticals Inc COM 56854Q200   7,934,128 985,606 SH   SOLE   985,606 0 0
Merck & Co Inc COM 58933Y105   74,989,192 728,404 SH   SOLE   728,404 0 0
Mirum Pharmaceuticals Inc COM 604749101   287,212 9,089 SH   SOLE   9,089 0 0
MoonLake Immunotherapeutics CLASS A ORD 61559X104   16,689,885 292,805 SH   SOLE   292,805 0 0
Replimune Group Inc COM 76029N106   5,357,141 313,100 SH Put SOLE   313,100 0 0
Replimune Group Inc COM 76029N106   4,277,500 250,000 SH Call SOLE   250,000 0 0
Replimune Group Inc COM 76029N106   8,620,771 503,844 SH   SOLE   503,844 0 0
Sanofi SPONSORED ADR 80105N105   37,299,915 695,375 SH   SOLE   695,375 0 0
Sarepta Therapeutics Inc COM 803607100   6,194,342 51,100 SH Call SOLE   51,100 0 0
Savara Inc COM 805111101   596,892 157,908 SH   SOLE   157,908 0 0
Shockwave Med Inc COM Shockwave   16,201,364 81,373 SH   SOLE   81,373 0 0
SPDR S&P 500 ETF Trust TR UNIT 78462F103   21,374,000 50,000 SH Put SOLE   50,000 0 0
Spruce Biosciences Inc COM 85209E109   131,146 58,029 SH   SOLE   58,029 0 0
Structure Therapeutics Inc SPONSORED ADS 86366E106   10,190,840 202,119 SH   SOLE   202,119 0 0
Stryker Corporation COM 863667101   896,052 3,279 SH   SOLE   3,279 0 0
Syndax Pharmaceuticals Inc COM 87164F105   6,534,000 450,000 SH Put SOLE   450,000 0 0
Syndax Pharmaceuticals Inc COM 87164F105   4,356,000 300,000 SH Call SOLE   300,000 0 0
Syndax Pharmaceuticals Inc COM 87164F105   13,675,183 941,817 SH   SOLE   941,817 0 0
Syndax Pharmaceuticals Inc COM 87164F105   4,356,000 300,000 SH Call SOLE   300,000 0 0
Zentalis Pharmaceuticals Inc COM 98943L107   24,305,518 1,211,641 SH   SOLE   1,211,641 0 0
argenx SE SPONSORED ADR 04016X101   38,438,583 78,186 SH   SOLE   78,186 0 0
Aerovate Therapeutics Inc COM 008064107   51,005,369 3,758,686 SH   SOLE   3,758,686 0 0
Ascendis Pharma A/S SPONSORED ADR 04351P101   70,607,556 754,032 SH   SOLE   754,032 0 0
Bolt Biotherapeutics Inc COM 097702104   2,864,614 2,754,437 SH   SOLE   2,754,437 0 0
Fusion Pharmaceuticals Inc COM 36118A100   304,457 117,099 SH   SOLE   117,099 0 0
Galera Therapeutics Inc COM 36338D108   539,958 3,083,712 SH   SOLE   3,083,712 0 0
Ikena Oncology Inc COM 45175G108   501,033 115,712 SH   SOLE   115,712 0 0
Inozyme Pharma Inc COM 45790W108   17,977,294 4,280,308 SH   SOLE   4,280,308 0 0
Karuna Therapeutics Inc COM 48576A100   233,422,996 1,380,466 SH   SOLE   1,380,466 0 0
Natera Inc COM 632307104   137,199,780 3,100,560 SH   SOLE   3,100,560 0 0
Nextcure Inc COM 65343E108   3,446,694 2,671,856 SH   SOLE   2,671,856 0 0
Nucana PLC SPONSORED ADR 67022C106   3,415,999 5,599,999 SH   SOLE   5,599,999 0 0
Nucana PLC COMMON SHARES GB00BYWYV   1,464,000 2,400,000 SH   SOLE   2,400,000 0 0
PDS Biotechnology Corp COM 70465T107   720,307 142,635 SH   SOLE   142,635 0 0
RayzeBio Inc COM 75525N107   53,713,522 2,419,528 SH   SOLE   2,419,528 0 0
Synlogic Inc COM 87166L209   107,710 38,331 SH   SOLE   38,331 0 0
Vera Therapeutics Inc CL A 92337R101   47,534,709 3,467,156 SH   SOLE   3,467,156 0 0
Y-mAbs Therapeutics Inc COM 984241109   11,958,815 2,194,278 SH   SOLE   2,194,278 0 0