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Basis of Presentation and Summary of Significant Accounting Policies - Additional Information (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2015
Sep. 30, 2015
Dec. 31, 2014
Accounting Policies [Abstract]      
Money market funds $ 194,500 $ 194,500  
Research and development costs 2,500 3,300  
Restricted Cash and Cash Equivalents Items [Line Items]      
Restricted cash and cash equivalents 3,833 3,833  
Non-current restricted cash 2,511 2,511 $ 0
Current restricted cash 1,322 1,322 $ 0
Letters of credit for facility leases      
Restricted Cash and Cash Equivalents Items [Line Items]      
Restricted cash and cash equivalents 3,710 3,710  
Other      
Restricted Cash and Cash Equivalents Items [Line Items]      
Restricted cash and cash equivalents $ 123 $ 123