Stock-Based Compensation (Tables)

9 Months Ended

Sep. 30, 2022

Share Based Compensation Arrangement By Share Based Payment Award [Line Items]

Summary of RSUs Activity Under the Plan

Total stock-based compensation expense related to stock options, RSUs and the 2020 ESPP by function was as follows:

	Three Months Ended September 30,				Nine Months Ended September 30,
	2022		2021		2022		2021
	(in thousands)				(in thousands)
Research and development	$	4,804	$	3,385	$	13,203	$	8,374
General and administrative		3,334		2,442		9,677		6,153
Total	$	8,138	$	5,827	$	22,880	$	14,527

2020 Plan and 2014 Plan

Share Based Compensation Arrangement By Share Based Payment Award [Line Items]

Summary of Option Activity Under the Plan

The following summarizes option activity under both the 2020 Plan and the 2014 Plan:

	Number of Shares underlying options			Weighted- average exercise price		Weighted- average remaining contractual term		Aggregate intrinsic value
						(in years)		(in thousands)
Balance, December 31, 2021		6,050,938		$	14.88		7.74	$	83,953
Options granted		2,552,340			19.30
Options exercised		(167,814	)		4.47
Options cancelled		(275,572	)		27.60
Balance, September 30, 2022		8,159,892		$	16.05		7.71	$	59,055
Options vested and expected to vest as of September 30, 2022		8,159,892		$	16.05		7.71	$	59,055
Options vested and exercisable as of September 30, 2022		4,207,766		$	10.86		6.70	$	48,420

2020 Equity Incentive Plan

Share Based Compensation Arrangement By Share Based Payment Award [Line Items]

Summary of RSUs Activity Under the Plan

Activity under the 2020 Plan with respect to the Company’s restricted stock units (RSUs) during the three months ended September 30, 2022 was as follows:

	Number of Shares			Weighted- average grant date fair value per share		Weighted- average remaining contractual term		Aggregate intrinsic value
						(in years)		(in thousands)
Balance, December 31, 2021		423,621		$	37.16		3.16	$	10,663
Restricted stock units granted		1,045,303
Restricted stock units vested		(194,052	)
Restricted stock units forfeited		(81,271	)
Balance, September 30, 2022		1,193,601		$	23.64		1.72		23,263
Expected to vest as of September 30, 2022		1,193,601		$	23.64		1.72		23,263