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Equity Method Investment (Details) - USD ($)
$ in Thousands
3 Months Ended 12 Months Ended
Mar. 31, 2023
Mar. 31, 2022
Dec. 31, 2022
Schedule of Equity Method Investments [Line Items]      
Loss from equity method investment $ 1,731 $ 1,041  
Net loss $ (7,873) (8,297)  
Angel Pharmaceuticals      
Schedule of Equity Method Investments [Line Items]      
Ownership interest (as percent) 49.70%   49.70%
Equity reserved (as percent) 7.00%   7.00%
Loss from equity method investment $ 1,700   $ (1,000)
Net loss (2,032) (1,325)  
Share of loss from investments accounted for using the equity method $ (1,731) $ (1,041)