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CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Cash flows from operating activities    
Net loss $ (8,297) $ (11,580)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 87 137
Accretion related to marketable securities 55 95
Stock-based compensation 739 1,225
Loss from equity method investment 1,041 100
Changes in operating assets and liabilities:    
Accounts receivable - related party 134  
Prepaid and other current assets 304 237
Operating lease right-of-use asset 238 193
Other assets   (664)
Accounts payable 624 1,443
Accrued and other liabilities (1,095) 287
Operating lease liability (254) (260)
Net cash used in operating activities (6,424) (8,787)
Cash flows from investing activities    
Purchases of marketable securities (26,384) (3,321)
Maturities of marketable securities 810 8,167
Net cash provided by (used in) investing activities (25,574) 4,846
Cash flows from financing activities    
Proceeds from issuance of common stock, net (includes $4,850 in aggregate gross proceeds from related parties for the three months ended March 31, 2021)   31,989
Proceeds from issuance of common stock in connection with at-the-market offering, net   601
Net cash provided by financing activities   32,590
Net increase (decrease) in cash and cash equivalents (31,998) 28,649
Cash and cash equivalents at beginning of the period 63,458 16,455
Cash and cash equivalents at end of the period $ 31,460 $ 45,104