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Note 2 - Significant Accounting Policies - Share-based Compensation Expense (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2024
Sep. 30, 2023
Sep. 30, 2024
Sep. 30, 2023
Share-based compensation expense $ 365 $ 955 $ 1,125 $ 2,574
Research and Development Expense [Member]        
Share-based compensation expense 242 824 738 2,235
General and Administrative Expense [Member]        
Share-based compensation expense $ 123 $ 131 $ 387 $ 339