Note 9 - Income Taxes - Reconciliation of Canadian Federal Statutory Income Tax Rate (Details)	12 Months Ended
Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Income tax benefit computed at federal tax rate	27.00%	27.00%	27.00%
Capital gains and foreign exchange	0.00%	1.20%	(13.00%)
Change in valuation allowance	4.10%	(37.30%)	(6.30%)
Tax Credits generated	1.60%	34.50%	0.00%
Prior year adjustments	1.10%	1.70%	(0.40%)
Changes in Uncertain Tax Positions	(1.50%)	(7.70%)	0.20%
Stock compensation and other	(0.70%)	(6.90%)	(0.60%)
Total	31.60%	12.50%	6.90%

Percentage of current income tax expense (benefit) and deferred income tax expense (benefit) pertaining to continuing operations.

Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 740
-SubTopic 10
-Section 50
-Paragraph 12
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Percentage of domestic federal statutory tax rate applicable to pretax income (loss).

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to changes in the valuation allowance for deferred tax assets.

+ References

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to revisions of previously reported income tax expense.

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Reference 1: http://www.xbrl.org/2009/role/commonPracticeRef
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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to income tax contingencies. Includes, but not limited to, domestic tax contingency, foreign tax contingency, state and local tax contingency, and other contingencies.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the domestic federal statutory income tax rates to pretax income (loss) from continuing operations attributable to tax credits. Including, but not limited to, research credit, foreign tax credit, investment tax credit, and other tax credits.

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Percentage of the difference between reported income tax expense (benefit) and expected income tax expense (benefit) computed by applying the federal statutory income tax rates to pretax income (loss) from continuing operations attributable to stock compensation and other exempt from income taxes.

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