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Note 4 - Accrued Expenses (Tables)
12 Months Ended
Dec. 31, 2017
Notes Tables  
Schedule of Accrued Liabilities [Table Text Block]
    2017   2016
Accrued compensation and related expenses   $
234
    $
413
 
Accrued professional fees    
32
     
95
 
Accrued building construction fees    
-
     
521
 
Accrued clinical trial expenses    
766
     
2,402
 
Other    
30
     
101
 
Total   $
1,062
    $
3,532