The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete. | |||||||||||||||||
UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 13F FORM 13F INFORMATION TABLE |
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COLUMN 1 | COLUMN 2 | COLUMN 3 | COLUMN 4 | COLUMN 5 | COLUMN 6 | COLUMN 7 | COLUMN 8 | ||||
VALUE | SHRS OR | SH/ | PUT/ | INVESTMENT | OTHER | VOTING AUTHORITY | |||||
NAME OF ISSUER | TITLE OF CLASS | CUSIP | (x$1000) | PRN AMT | PRN | CALL | DISCRETION | MANAGER | SOLE | SHARED | NONE |
ABBVIE INC | COM | 00287Y109 | 6,368 | 107,500 | SH | DFND | 2 | 0 | 0 | 107,500 | |
ACADIA HEALTHCARE PANY IN | COM | 00404A109 | 3,123 | 50,000 | SH | DFND | 2 | 0 | 0 | 50,000 | |
ACADIA PHARMACEUTICALS INC | COM | 004225108 | 727 | 20,390 | SH | DFND | 2 | 0 | 0 | 20,390 | |
ACCELERON PHARMA INC | COM | 00434H108 | 800 | 16,400 | SH | DFND | 2 | 0 | 0 | 16,400 | |
ACORDA THERAPEUTICS INC | COM | 00484M106 | 428 | 10,000 | SH | DFND | 2 | 0 | 0 | 10,000 | |
ADVANCED SEMICONDUCTOR ENGR | SPONSORED ADR | 00756M404 | 84 | 14,800 | SH | DFND | 1 | 14,800 | 0 | 0 | |
ADVANCED SEMICONDUCTOR ENGR | SPONSORED ADR | 00756M404 | 130 | 23,000 | SH | DFND | 2 | 0 | 0 | 23,000 | |
AERIE PHARMACEUTICALS INC | COM | 00771V108 | 4,675 | 192,006 | SH | DFND | 2 | 0 | 0 | 192,006 | |
AIR METHODS CORP | COM PAR $.06 | 009128307 | 10,639 | 253,736 | SH | DFND | 2 | 0 | 0 | 253,736 | |
ALEXION PHARMACEUTICALS INC | COM | 015351109 | 7,861 | 41,211 | SH | DFND | 2 | 0 | 0 | 41,211 | |
ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 | 10,856 | 133,580 | SH | DFND | 2 | 0 | 0 | 133,580 | |
ALIBABA GROUP HLDG LTD | SPONSORED ADS | 01609W102 | 873 | 10,740 | SH | DFND | 1 | 10,740 | 0 | 0 | |
ALLERGAN PLC | SHS | G0177J108 | 42,701 | 136,642 | SH | DFND | 2 | 0 | 0 | 136,642 | |
ALLIANCE DATA SYSTEMS CORP | COM | 018581108 | 134,571 | 486,570 | SH | DFND | 2 | 222,760 | 0 | 263,810 | |
ALLIANCE DATA SYSTEMS CORP | COM | 018581108 | 13,198 | 47,720 | SH | DFND | 1 | 47,720 | 0 | 0 | |
ALPHABET INC | CAP STK CL C ADDED | 02079K107 | 289,627 | 381,651 | SH | DFND | 2 | 169,640 | 0 | 212,011 | |
ALPHABET INC | CAP STK CL C ADDED | 02079K107 | 27,376 | 36,074 | SH | DFND | 1 | 36,074 | 0 | 0 | |
ALPHABET INC | CAP STK CL A ADDED | 02079K305 | 46,464 | 59,721 | SH | DFND | 2 | 32,460 | 0 | 27,261 | |
ALPHABET INC | CAP STK CL A ADDED | 02079K305 | 6,559 | 8,430 | SH | DFND | 1 | 8,430 | 0 | 0 | |
AMERICAN INTL GROUP INC | COM NEW | 026874784 | 236,842 | 3,821,885 | SH | DFND | 2 | 1,768,020 | 0 | 2,053,865 | |
AMERICAN INTL GROUP INC | COM NEW | 026874784 | 24,638 | 397,580 | SH | DFND | 1 | 397,580 | 0 | 0 | |
AMERISOURCEBERGEN CORP | COM | 03073E105 | 289 | 2,790 | SH | DFND | 1 | 2,790 | 0 | 0 | |
AMERISOURCEBERGEN CORP | COM | 03073E105 | 8,536 | 82,310 | SH | DFND | 2 | 0 | 0 | 82,310 | |
AMGEN INC | COM | 031162100 | 38,462 | 236,938 | SH | DFND | 2 | 0 | 0 | 236,938 | |
APPLIED GENETIC TECHNOL CORP | COM | 03820J100 | 1,428 | 70,000 | SH | DFND | 2 | 0 | 0 | 70,000 | |
AUTOZONE INC | COM | 053332102 | 391 | 527 | SH | DFND | 1 | 527 | 0 | 0 | |
AUTOZONE INC | COM | 053332102 | 415 | 560 | SH | DFND | 2 | 0 | 0 | 560 | |
BAIDU INC | SPON ADR REP A | 056752108 | 9,962 | 52,700 | SH | DFND | 2 | 0 | 0 | 52,700 | |
BAIDU INC | SPON ADR REP A | 056752108 | 821 | 4,345 | SH | DFND | 1 | 4,345 | 0 | 0 | |
BIOGEN INC | COM | 09062X103 | 28,719 | 93,747 | SH | DFND | 2 | 0 | 0 | 93,747 | |
BIOMARIN PHARMACEUTICAL INC | COM | 09061G101 | 13,365 | 127,575 | SH | DFND | 2 | 0 | 0 | 127,575 | |
BLUEBIRD BIO INC | COM | 09609G100 | 321 | 5,000 | SH | DFND | 2 | 0 | 0 | 5,000 | |
CARA THERAPEUTICS INC | COM | 140755109 | 4,417 | 262,000 | SH | DFND | 2 | 0 | 0 | 262,000 | |
CELGENE CORP | COM | 151020104 | 44,412 | 370,838 | SH | DFND | 2 | 0 | 0 | 370,838 | |
CEMPRA INC | COM | 15130J109 | 24,497 | 786,930 | SH | DFND | 2 | 0 | 0 | 786,930 | |
CENTENE CORP DEL | COM | 15135B101 | 23,757 | 361,000 | SH | DFND | 2 | 0 | 0 | 361,000 | |
CEPHEID | COM | 15670R107 | 4,289 | 117,400 | SH | DFND | 2 | 0 | 0 | 117,400 | |
CERNER CORP | COM | 156782104 | 554 | 9,200 | SH | DFND | 1 | 9,200 | 0 | 0 | |
CERNER CORP | COM | 156782104 | 560 | 9,300 | SH | DFND | 2 | 0 | 0 | 9,300 | |
CHIMERIX INC | COM | 16934W106 | 1,181 | 132,000 | SH | DFND | 2 | 0 | 0 | 132,000 | |
CIGNA CORPORATION | COM | 125509109 | 19,133 | 130,750 | SH | DFND | 2 | 0 | 0 | 130,750 | |
CITIGROUP INC | COM NEW | 172967424 | 219,215 | 4,236,040 | SH | DFND | 2 | 1,936,690 | 0 | 2,299,350 | |
CITIGROUP INC | COM NEW | 172967424 | 21,994 | 425,010 | SH | DFND | 1 | 425,010 | 0 | 0 | |
COHERUS BIOSCIENCES INC | COM | 19249H103 | 3,352 | 146,000 | SH | DFND | 2 | 0 | 0 | 146,000 | |
COMCAST CORP NEW | CL A | 20030N101 | 480 | 8,500 | SH | DFND | 2 | 0 | 0 | 8,500 | |
COMCAST CORP NEW | CL A | 20030N101 | 530 | 9,390 | SH | DFND | 1 | 9,390 | 0 | 0 | |
COOPER COS INC | COM NEW | 216648402 | 8,012 | 59,700 | SH | DFND | 2 | 0 | 0 | 59,700 | |
CREDICORP LTD | COM | G2519Y108 | 47 | 485 | SH | DFND | 2 | 0 | 0 | 485 | |
CREDICORP LTD | COM | G2519Y108 | 40 | 415 | SH | DFND | 1 | 415 | 0 | 0 | |
CVS HEALTH CORP | COM | 126650100 | 273,108 | 2,793,370 | SH | DFND | 2 | 1,268,200 | 0 | 1,525,170 | |
CVS HEALTH CORP | COM | 126650100 | 28,658 | 293,120 | SH | DFND | 1 | 293,120 | 0 | 0 | |
DANAHER CORP DEL | COM | 235851102 | 443 | 4,770 | SH | DFND | 1 | 4,770 | 0 | 0 | |
DANAHER CORP DEL | COM | 235851102 | 372 | 4,000 | SH | DFND | 2 | 0 | 0 | 4,000 | |
DAVITA HEALTHCARE PARTNERS I | COM | 23918K108 | 6,671 | 95,691 | SH | DFND | 2 | 0 | 0 | 95,691 | |
DEX INC | COM | 252131107 | 4,089 | 49,925 | SH | DFND | 2 | 0 | 0 | 49,925 | |
DISCOVER FINL SVCS | COM | 254709108 | 456 | 8,500 | SH | DFND | 2 | 0 | 0 | 8,500 | |
DISCOVER FINL SVCS | COM | 254709108 | 408 | 7,610 | SH | DFND | 1 | 7,610 | 0 | 0 | |
DOLLAR GEN CORP NEW | COM | 256677105 | 1,042 | 14,500 | SH | DFND | 1 | 14,500 | 0 | 0 | |
DOLLAR GEN CORP NEW | COM | 256677105 | 1,028 | 14,300 | SH | DFND | 2 | 0 | 0 | 14,300 | |
DUKE ENERGY CORP NEW | COM NEW | 26441C204 | 792 | 11,100 | SH | DFND | 1 | 11,100 | 0 | 0 | |
DUKE ENERGY CORP NEW | COM NEW | 26441C204 | 778 | 10,900 | SH | DFND | 2 | 0 | 0 | 10,900 | |
DYNAVAX TECHNOLOGIES CORP | COM NEW | 268158201 | 4,454 | 184,362 | SH | DFND | 2 | 0 | 0 | 184,362 | |
EAGLE PHARMACEUTICALS INC | COM | 269796108 | 19,410 | 218,907 | SH | DFND | 2 | 0 | 0 | 218,907 | |
ECOLAB INC | COM | 278865100 | 305,031 | 2,666,821 | SH | DFND | 2 | 1,231,240 | 0 | 1,435,581 | |
ECOLAB INC | COM | 278865100 | 31,707 | 277,210 | SH | DFND | 1 | 277,210 | 0 | 0 | |
EDISON INTL | COM | 281020107 | 799 | 13,500 | SH | DFND | 1 | 13,500 | 0 | 0 | |
EDISON INTL | COM | 281020107 | 793 | 13,400 | SH | DFND | 2 | 0 | 0 | 13,400 | |
ENBRIDGE INC | COM | 29250N105 | 796 | 17,300 | SH | DFND | 1 | 17,300 | 0 | 0 | |
ENBRIDGE INC | COM | 29250N105 | 736 | 16,000 | SH | DFND | 2 | 0 | 0 | 16,000 | |
ENDO INTL PLC | SHS | G30401106 | 1,071 | 17,500 | SH | DFND | 2 | 0 | 0 | 17,500 | |
ESPERION THERAPEUTICS INC NE | COM | 29664W105 | 423 | 19,000 | SH | DFND | 2 | 0 | 0 | 19,000 | |
EXACT SCIENCES CORP | COM | 30063P105 | 2,308 | 250,000 | SH | DFND | 2 | 0 | 0 | 250,000 | |
EXAMWORKS GROUP INC | COM | 30066A105 | 1,995 | 75,000 | SH | DFND | 2 | 0 | 0 | 75,000 | |
EXPRESS SCRIPTS HLDG CO | COM | 30219G108 | 577 | 6,600 | SH | DFND | 1 | 6,600 | 0 | 0 | |
EXPRESS SCRIPTS HLDG CO | COM | 30219G108 | 17,622 | 201,601 | SH | DFND | 2 | 0 | 0 | 201,601 | |
FACEBOOK INC | CL A | 30303M102 | 280,672 | 2,681,755 | SH | DFND | 2 | 1,239,780 | 0 | 1,441,975 | |
FACEBOOK INC | CL A | 30303M102 | 28,771 | 274,895 | SH | DFND | 1 | 274,895 | 0 | 0 | |
FIDELITY NATL INFORMATION SV | COM | 31620M106 | 830 | 13,700 | SH | DFND | 2 | 0 | 0 | 13,700 | |
FIDELITY NATL INFORMATION SV | COM | 31620M106 | 879 | 14,500 | SH | DFND | 1 | 14,500 | 0 | 0 | |
FIRST REP BK SAN FRANCISCO C | COM | 33616C100 | 495 | 7,500 | SH | DFND | 1 | 7,500 | 0 | 0 | |
FIRST REP BK SAN FRANCISCO C | COM | 33616C100 | 456 | 6,900 | SH | DFND | 2 | 0 | 0 | 6,900 | |
FLEX PHARMA INC | COM | 33938A105 | 1,868 | 150,000 | SH | DFND | 2 | 0 | 0 | 150,000 | |
GILEAD SCIENCES INC | COM | 375558103 | 333,934 | 3,300,072 | SH | DFND | 2 | 1,260,980 | 0 | 2,039,092 | |
GILEAD SCIENCES INC | COM | 375558103 | 28,406 | 280,720 | SH | DFND | 1 | 280,720 | 0 | 0 | |
HCA HOLDINGS INC | COM | 40412C101 | 10,961 | 162,075 | SH | DFND | 2 | 0 | 0 | 162,075 | |
HDFC BANK LTD | ADR REPS 3 SHS | 40415F101 | 138,578 | 2,249,650 | SH | DFND | 2 | 2,176,800 | 0 | 72,850 | |
HDFC BANK LTD | ADR REPS 3 SHS | 40415F101 | 5,218 | 84,700 | SH | DFND | 1 | 84,700 | 0 | 0 | |
HOME DEPOT INC | COM | 437076102 | 39,264 | 296,890 | SH | DFND | 1 | 296,890 | 0 | 0 | |
HOME DEPOT INC | COM | 437076102 | 381,865 | 2,887,450 | SH | DFND | 2 | 1,314,680 | 0 | 1,572,770 | |
HORIZON PHARMA PLC | SHS | G4617B105 | 14,335 | 661,500 | SH | DFND | 2 | 0 | 0 | 661,500 | |
HUMANA INC | COM | 444859102 | 1,321 | 7,400 | SH | DFND | 2 | 0 | 0 | 7,400 | |
ICICI BK LTD | ADR | 45104G104 | 21,298 | 2,720,090 | SH | DFND | 2 | 0 | 0 | 2,720,090 | |
ICICI BK LTD | ADR | 45104G104 | 1,644 | 209,950 | SH | DFND | 1 | 209,950 | 0 | 0 | |
INFINITY PHARMACEUTICALS INC | COM | 45665G303 | 319 | 40,680 | SH | DFND | 2 | 0 | 0 | 40,680 | |
INGREDION INC | COM | 457187102 | 546 | 5,700 | SH | DFND | 1 | 5,700 | 0 | 0 | |
INGREDION INC | COM | 457187102 | 594 | 6,200 | SH | DFND | 2 | 0 | 0 | 6,200 | |
INNOCOLL AG | SPONSORED ADR | 45780Q103 | 2,450 | 295,184 | SH | DFND | 2 | 0 | 0 | 295,184 | |
INSULET CORP | COM | 45784P101 | 5,596 | 148,000 | SH | DFND | 2 | 0 | 0 | 148,000 | |
INTERCEPT PHARMACEUTICALS IN | COM | 45845P108 | 568 | 3,800 | SH | DFND | 2 | 0 | 0 | 3,800 | |
INTRA CELLULAR THERAPIES INC | COM | 46116X101 | 6,670 | 124,000 | SH | DFND | 2 | 0 | 0 | 124,000 | |
IONIS PHARMACEUTICALS INC | COM ADDED | 462222100 | 4,710 | 76,060 | SH | DFND | 2 | 0 | 0 | 76,060 | |
JAZZ PHARMACEUTICALS PLC | SHS USD | G50871105 | 13,309 | 94,689 | SH | DFND | 2 | 0 | 0 | 94,689 | |
JOHNSON & JOHNSON | COM | 478160104 | 28,298 | 275,486 | SH | DFND | 2 | 0 | 0 | 275,486 | |
JOHNSON & JOHNSON | COM | 478160104 | 746 | 7,265 | SH | DFND | 1 | 7,265 | 0 | 0 | |
JPMORGAN CHASE & CO | COM | 46625H100 | 726 | 11,000 | SH | DFND | 1 | 11,000 | 0 | 0 | |
JPMORGAN CHASE & CO | COM | 46625H100 | 759 | 11,500 | SH | DFND | 2 | 0 | 0 | 11,500 | |
K2M GROUP HLDGS INC | COM | 48273J107 | 1,997 | 101,151 | SH | DFND | 2 | 0 | 0 | 101,151 | |
KEMPHARM INC | COM | 488445107 | 3,277 | 165,000 | SH | DFND | 2 | 0 | 0 | 165,000 | |
KERYX BIOPHARMACEUTICALS INC | COM | 492515101 | 2,127 | 421,110 | SH | DFND | 2 | 0 | 0 | 421,110 | |
KITE PHARMA INC | COM | 49803L109 | 2,896 | 47,000 | SH | DFND | 2 | 0 | 0 | 47,000 | |
KROGER CO | COM | 501044101 | 247 | 5,900 | SH | DFND | 1 | 5,900 | 0 | 0 | |
KROGER CO | COM | 501044101 | 213 | 5,100 | SH | DFND | 2 | 0 | 0 | 5,100 | |
L BRANDS INC | COM | 501797104 | 314,355 | 3,280,685 | SH | DFND | 2 | 1,498,560 | 0 | 1,782,125 | |
L BRANDS INC | COM | 501797104 | 32,040 | 334,380 | SH | DFND | 1 | 334,380 | 0 | 0 | |
LDR HLDG CORP | COM | 50185U105 | 4,191 | 166,917 | SH | DFND | 2 | 0 | 0 | 166,917 | |
LILLY ELI & CO | COM | 532457108 | 303 | 3,600 | SH | DFND | 1 | 3,600 | 0 | 0 | |
LILLY ELI & CO | COM | 532457108 | 295 | 3,500 | SH | DFND | 2 | 0 | 0 | 3,500 | |
MASTERCARD INC | CL A | 57636Q104 | 2,726 | 28,000 | SH | DFND | 2 | 0 | 0 | 28,000 | |
MCKESSON CORP | COM | 58155Q103 | 225,612 | 1,143,902 | SH | DFND | 2 | 525,570 | 0 | 618,332 | |
MCKESSON CORP | COM | 58155Q103 | 24,536 | 124,405 | SH | DFND | 1 | 124,405 | 0 | 0 | |
MEDIVATION INC | COM | 58501N101 | 4,460 | 92,262 | SH | DFND | 2 | 0 | 0 | 92,262 | |
MEDNAX INC | COM | 58502B106 | 645 | 9,000 | SH | DFND | 2 | 0 | 0 | 9,000 | |
MEDNAX INC | COM | 58502B106 | 573 | 8,000 | SH | DFND | 1 | 8,000 | 0 | 0 | |
MEDTRONIC PLC | SHS | G5960L103 | 631 | 8,200 | SH | DFND | 1 | 8,200 | 0 | 0 | |
MEDTRONIC PLC | SHS | G5960L103 | 738 | 9,600 | SH | DFND | 2 | 0 | 0 | 9,600 | |
MERCK & CO INC NEW | COM | 58933Y105 | 10,796 | 204,397 | SH | DFND | 2 | 0 | 0 | 204,397 | |
MIMEDX GROUP INC | COM | 602496101 | 1,874 | 200,000 | SH | DFND | 2 | 0 | 0 | 200,000 | |
MONDELEZ INTL INC | CL A | 609207105 | 578 | 12,900 | SH | DFND | 2 | 0 | 0 | 12,900 | |
MONDELEZ INTL INC | CL A | 609207105 | 610 | 13,600 | SH | DFND | 1 | 13,600 | 0 | 0 | |
NEWLINK GENETICS CORP | COM | 651511107 | 482 | 13,235 | SH | DFND | 2 | 0 | 0 | 13,235 | |
NEXTERA ENERGY INC | COM | 65339F101 | 457 | 4,400 | SH | DFND | 2 | 0 | 0 | 4,400 | |
NEXTERA ENERGY INC | COM | 65339F101 | 468 | 4,500 | SH | DFND | 1 | 4,500 | 0 | 0 | |
NIKE INC | CL B | 654106103 | 8,469 | 135,500 | SH | DFND | 2 | 0 | 0 | 135,500 | |
NIKE INC | CL B | 654106103 | 2,286 | 36,580 | SH | DFND | 1 | 36,580 | 0 | 0 | |
NOVADAQ TECHNOLOGIES INC | COM | 66987G102 | 3,822 | 300,000 | SH | DFND | 2 | 0 | 0 | 300,000 | |
NUVASIVE INC | COM | 670704105 | 2,065 | 38,160 | SH | DFND | 2 | 0 | 0 | 38,160 | |
OXFORD IMMUNOTEC GLOBAL PLC | ORD SHS | G6855A103 | 837 | 70,460 | SH | DFND | 2 | 0 | 0 | 70,460 | |
PFIZER INC | COM | 717081103 | 37,087 | 1,148,915 | SH | DFND | 2 | 0 | 0 | 1,148,915 | |
PG&E CORP | COM | 69331C108 | 606 | 11,400 | SH | DFND | 2 | 0 | 0 | 11,400 | |
PG&E CORP | COM | 69331C108 | 628 | 11,810 | SH | DFND | 1 | 11,810 | 0 | 0 | |
PORTOLA PHARMACEUTICALS INC | COM | 737010108 | 2,650 | 51,513 | SH | DFND | 2 | 0 | 0 | 51,513 | |
PTC THERAPEUTICS INC | COM | 69366J200 | 2,064 | 63,700 | SH | DFND | 2 | 0 | 0 | 63,700 | |
RADIUS HEALTH INC | COM NEW | 750469207 | 1,128 | 18,330 | SH | DFND | 2 | 0 | 0 | 18,330 | |
REGENERON PHARMACEUTICALS | COM | 75886F107 | 1,591 | 2,930 | SH | DFND | 2 | 0 | 0 | 2,930 | |
REGULUS THERAPEUTICS INC | COM | 75915K101 | 1,395 | 160,000 | SH | DFND | 2 | 0 | 0 | 160,000 | |
RELYPSA INC | COM | 759531106 | 8,304 | 293,000 | SH | DFND | 2 | 0 | 0 | 293,000 | |
REYNOLDS AMERICAN INC | COM | 761713106 | 199,682 | 4,326,800 | SH | DFND | 2 | 2,286,700 | 0 | 2,040,100 | |
REYNOLDS AMERICAN INC | COM | 761713106 | 20,684 | 448,200 | SH | DFND | 1 | 448,200 | 0 | 0 | |
SENSATA TECHNOLOGIES HLDG NV | SHS | N7902X106 | 118,368 | 2,569,860 | SH | DFND | 2 | 1,218,700 | 0 | 1,351,160 | |
SENSATA TECHNOLOGIES HLDG NV | SHS | N7902X106 | 11,503 | 249,750 | SH | DFND | 1 | 249,750 | 0 | 0 | |
SERVICE CORP INTL | COM | 817565104 | 755 | 29,000 | SH | DFND | 1 | 29,000 | 0 | 0 | |
SERVICE CORP INTL | COM | 817565104 | 734 | 28,200 | SH | DFND | 2 | 0 | 0 | 28,200 | |
SHIRE PLC | SPONSORED ADR | 82481R106 | 21,386 | 104,324 | SH | DFND | 2 | 0 | 0 | 104,324 | |
SNAP ON INC | COM | 833034101 | 245 | 1,430 | SH | DFND | 1 | 1,430 | 0 | 0 | |
SNAP ON INC | COM | 833034101 | 206 | 1,200 | SH | DFND | 2 | 0 | 0 | 1,200 | |
SORRENTO THERAPEUTICS INC | COM NEW | 83587F202 | 1,942 | 222,981 | SH | DFND | 2 | 0 | 0 | 222,981 | |
SPARK THERAPEUTICS INC | COM | 84652J103 | 3,562 | 78,620 | SH | DFND | 2 | 0 | 0 | 78,620 | |
SPECTRANETICS CORP | COM | 84760C107 | 3,297 | 218,956 | SH | DFND | 2 | 0 | 0 | 218,956 | |
SUPERNUS PHARMACEUTICALS INC | COM | 868459108 | 3,199 | 238,000 | SH | DFND | 2 | 0 | 0 | 238,000 | |
TAIWAN SEMICONDUCTOR MFG LTD | SPONSORED ADR | 874039100 | 4,998 | 219,700 | SH | DFND | 2 | 204,700 | 0 | 15,000 | |
TAIWAN SEMICONDUCTOR MFG LTD | SPONSORED ADR | 874039100 | 240 | 10,560 | SH | DFND | 1 | 10,560 | 0 | 0 | |
TARGET CORP | COM | 87612E106 | 385 | 5,300 | SH | DFND | 1 | 5,300 | 0 | 0 | |
TARGET CORP | COM | 87612E106 | 428 | 5,900 | SH | DFND | 2 | 0 | 0 | 5,900 | |
TD AMERITRADE HLDG CORP | COM | 87236Y108 | 14,991 | 431,900 | SH | DFND | 1 | 431,900 | 0 | 0 | |
TD AMERITRADE HLDG CORP | COM | 87236Y108 | 151,080 | 4,352,650 | SH | DFND | 2 | 2,004,800 | 0 | 2,347,850 | |
TETRAPHASE PHARMACEUTICALS I | COM | 88165N105 | 6,274 | 625,510 | SH | DFND | 2 | 0 | 0 | 625,510 | |
TEVA PHARMACEUTICAL INDS LTD | ADR | 881624209 | 20,874 | 318,000 | SH | DFND | 2 | 0 | 0 | 318,000 | |
THERMO FISHER SCIENTIFIC INC | COM | 883556102 | 312 | 2,200 | SH | DFND | 2 | 0 | 0 | 2,200 | |
THERMO FISHER SCIENTIFIC INC | COM | 883556102 | 346 | 2,440 | SH | DFND | 1 | 2,440 | 0 | 0 | |
TORONTO DOMINION BK ONT | COM NEW | 891160509 | 891 | 16,420 | SH | DFND | 1 | 16,420 | 0 | 0 | |
TORONTO DOMINION BK ONT | COM NEW | 891160509 | 868 | 16,000 | SH | DFND | 2 | 0 | 0 | 16,000 | |
TRANSENTERIX INC | COM NEW | 89366M201 | 1,580 | 637,169 | SH | DFND | 2 | 0 | 0 | 637,169 | |
TROVAGENE INC | COM NEW | 897238309 | 1,774 | 328,584 | SH | DFND | 2 | 0 | 0 | 328,584 | |
ULTRAGENYX PHARMACEUTICAL IN | COM | 90400D108 | 4,487 | 40,000 | SH | DFND | 2 | 0 | 0 | 40,000 | |
UNION PAC CORP | COM | 907818108 | 152 | 1,940 | SH | DFND | 2 | 0 | 0 | 1,940 | |
UNITEDHEALTH GROUP INC | COM | 91324P102 | 647 | 5,500 | SH | DFND | 1 | 5,500 | 0 | 0 | |
UNITEDHEALTH GROUP INC | COM | 91324P102 | 39,369 | 334,658 | SH | DFND | 2 | 0 | 0 | 334,658 | |
V F CORP | COM | 918204108 | 423 | 6,800 | SH | DFND | 2 | 0 | 0 | 6,800 | |
V F CORP | COM | 918204108 | 386 | 6,200 | SH | DFND | 1 | 6,200 | 0 | 0 | |
VALEANT PHARMACEUTICALS INTL | COM | 91911K102 | 16,413 | 161,461 | SH | DFND | 2 | 0 | 0 | 161,461 | |
VERIZON MUNICATIONS INC | COM | 92343V104 | 540 | 11,690 | SH | DFND | 1 | 11,690 | 0 | 0 | |
VERIZON MUNICATIONS INC | COM | 92343V104 | 337 | 7,300 | SH | DFND | 2 | 0 | 0 | 7,300 | |
VERTEX PHARMACEUTICALS INC | COM | 92532F100 | 2,705 | 21,500 | SH | DFND | 2 | 0 | 0 | 21,500 | |
VISA INC | COM CL A | 92826C839 | 59,620 | 768,790 | SH | DFND | 1 | 768,790 | 0 | 0 | |
VISA INC | COM CL A | 92826C839 | 582,440 | 7,510,510 | SH | DFND | 2 | 3,449,430 | 0 | 4,061,080 | |
WELLS FARGO & CO NEW | COM | 949746101 | 265,792 | 4,889,478 | SH | DFND | 2 | 2,209,540 | 0 | 2,679,938 | |
WELLS FARGO & CO NEW | COM | 949746101 | 27,737 | 510,240 | SH | DFND | 1 | 510,240 | 0 | 0 | |
ZELTIQ AESTHETICS INC | COM | 98933Q108 | 4,280 | 150,000 | SH | DFND | 2 | 0 | 0 | 150,000 |