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Consolidated Statements of Stockholders' Equity - USD ($)
$ in Thousands
Common Stock
Warrants [Member]
Common Stock
Rights Offering [Member]
Common Stock
Additional Paid-in Capital [Member]
Warrants [Member]
Additional Paid-in Capital [Member]
Rights Offering [Member]
Additional Paid-in Capital [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Warrants [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Rights Offering [Member]
Accumulated Other Comprehensive Income (Loss) [Member]
Accumulated Deficit [Member]
Warrants [Member]
Accumulated Deficit [Member]
Rights Offering [Member]
Accumulated Deficit [Member]
Initial Public Offering [Member]
Warrants [Member]
Warrants [Member]
Rights Offering [Member]
Total
Balance at Dec. 31, 2017     $ 17     $ 84,202     $ (51)     $ (38,173)       $ 45,995
Balance, shares at Dec. 31, 2017     16,819,000                          
Shares issued   $ 4     $ 44,782               $ 44,786  
Shares issued, shares   3,581,000                            
Issuance of shares upon exercise of stock options     498         498
Issuance of shares upon exercise of stock options, shares 24,000   145,000                          
Issuance of shares upon vesting of share-based compensation         327               327
Issuance of shares upon vesting of share-based compensation, shares     24,000                          
Stock-based compensation expense         12,338               12,338
Tax payments related to shares withheld for vested restricted stock units         (115)               (115)
Unrealized gain (loss) on available-for-sale securities             50           50
Net loss                 (37,545)       (37,545)
Balance at Dec. 31, 2018     $ 21     142,032     (1)     (75,718)       66,334
Balance, shares at Dec. 31, 2018     20,593,000                          
Issuance of shares upon exercise of stock options     272         272
Issuance of shares upon exercise of stock options, shares 37,000   99,000                          
Issuance of shares under employee stock purchase plan         423               423
Issuance of shares under employee stock purchase plan, shares     38,000                          
Issuance of shares upon vesting of restriced stock units                      
Issuance of shares upon vesting of restriced stock units, shares     58,000                          
Stock-based compensation expense         11,287               11,287
Tax payments related to shares withheld for vested restricted stock units         (613)               (613)
Unrealized gain (loss) on available-for-sale securities             5           5
Net loss                 (46,971)       (46,971)
Balance at Dec. 31, 2019     $ 21     153,401     4     (122,689)       $ 30,737
Balance, shares at Dec. 31, 2019     20,825,000                         20,825,000
Issuance of shares upon exercise of stock options         887               $ 887
Issuance of shares upon exercise of stock options, shares     175,000                   36,224 197,108   175,066
Issuance of shares under employee stock purchase plan         490               $ 490
Issuance of shares under employee stock purchase plan, shares     83,000                          
Issuance of shares upon exercise of warrants         1,127               1,127
Issuance of shares upon exercise of warrants, shares     187,000                          
Issuance of common stock and warrants in connection with rights offering, net of issuance cost of $565     $ 4     29,430               29,434
Issuance of common stock and warrants in connection with rights offering, net of issuance cost of $565, shares     4,280,000                          
Stock-based compensation expense         10,075               10,075
Unrealized gain (loss) on available-for-sale securities             (5)           (5)
Net loss                 (49,851)       (49,851)
Balance at Dec. 31, 2020     $ 25     $ 195,410     $ (1)     $ (172,540)       $ 22,894
Balance, shares at Dec. 31, 2020     25,550,000                         25,550,000