Common Stock and Common Stock Purchase Warrants (Details Narrative) - USD ($) $ / shares in Units, $ in Thousands			1 Months Ended	12 Months Ended
	Feb. 23, 2021	Jan. 05, 2021	Jan. 31, 2021	Dec. 31, 2021	Dec. 31, 2020
Accumulated Other Comprehensive Income (Loss) [Line Items]
Common shares authorized				150,000,000	150,000,000
Common stock, par value per share				$ 0.001	$ 0.001
Common stock, shares issued				86,367,845	63,819,935
Common stock, shares outstanding				86,367,845	63,819,935
Proceeds from issuance of common stock				$ 55,016	$ 16,032
Repayments of Convertible Debt				$ 14,816
Number of shares issued for exercise of warrants				4,881,429
Stock Issued During Period, Value, Stock Options Exercised				$ 979
Class of Warrant or Right, Exercise Price of Warrants or Rights				$ 1.70	$ 1.68
2014 Equity Plan [Member] | Equity Option [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period				621,164
Stock Issued During Period, Value, Stock Options Exercised				$ 980
Employee Stock Purchase Plan [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Stock Issued During Period, Shares, Employee Stock Purchase Plans				234,592	306,555
Series B Convertible Preferred Stock [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Convertible Preferred Stock, Shares Issued upon Conversion				210,448
Series W Warrants [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of common stock shares issued				3,945
Class of Warrant or Right, Exercise Price of Warrants or Rights				$ 5.00
Class of warrant or right issued				377,873
Class of warrant or right, outstanding				377,873
November 2019 Senior Convertible Notes [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Debt conversion shares issued			667,668
Repayments of Convertible Debt			$ 956
Debt Instrument, Periodic Payment, Interest			$ 7
December 2018 Senior Convertible Note and November 2019 Senior Convertible Notes [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Debt conversion shares issued					10,929,202
Common Stock [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Common shares authorized					150,000,000
Number of common stock shares issued	9,782,609	6,000,000			10,647,500
Proceeds from issuance of common stock	$ 41,566	$ 13,434			$ 17,036
Placement agent fees and legal fees		951			1,004
Debt Issuance Costs, Net	$ 290	$ 71			$ 100
Share-based Compensation Arrangement by Share-based Payment Award, Options, Exercises in Period				621,164
Stock Issued During Period, Value, Stock Options Exercised
Stock Issued During Period, Shares, Employee Stock Purchase Plans				234,592	306,555
Series Z Warrants [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of shares issued for exercise of warrants				4,877,484
[custom:NumberOfWarrantsExercised]				4,877,484
Class of Warrant or Right, Exercise Price of Warrants or Rights				$ 1.60
Warrant description				The Company may redeem the Series Z Warrants, at the Company’s option, in whole or in part, at a price of $0.01 per Series Z Warrant at any time while the Series Z Warrants are exercisable, upon a minimum of 30 days’ prior written notice of redemption, if, and only if, the volume weighted average closing price of the common stock of the Company equals or exceeds $9.00 (subject to adjustment) for any 20 out of 30 consecutive trading days ending three business days before the Company issues its notice of redemption, and provided the average daily trading volume in the common stock of the Company during such 30-day period is at least 20,000 shares per day; and if, and only if, there is a current registration statement in effect with respect to the shares of Common Stock underlying such Series Z Warrants.
Series W Warrants [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of shares issued for exercise of warrants				3,945