PAVMED INC.

One Grand Central Place, Suite 4600

New York, New York 10165

January 5, 2022

Securities and Exchange Commission

Division of Corporation Finance

Washington, District of Columbia 20549

Re:	PAVmed Inc.
	Registration Statement on Form S-3
	Filed December 21, 2021
	File No. 333-261814

Ladies and Gentlemen:

Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, PAVmed Inc. hereby requests acceleration of the effectiveness of the above-referenced Registration Statement (File No. 333-261814), so that such Registration Statement will become effective at 9:30 a.m. Eastern Time on Friday, January 7, 2022, or as soon thereafter as practicable.

Sincerely,
PAVMED INC.
By:	/s/ Dennis M. McGrath
Name:	Dennis M. McGrath
Title:	President and Chief Financial Officer