PAVMED INC.

One Grand Central Place

60 E.42 ^ND Street

Suite 4600

New York, New York 10165

May 22, 2018

Securities and Exchange Commission

Division of Corporation Finance

Washington, DC 20549

Re:	PAVmed Inc.
	Registration Statement on Form S-1
	Originally Filed January 17, 2018
	File No. 333-222581

Ladies and Gentlemen:

Pursuant to Rule 461 promulgated under the Securities Act of 1933, as amended, PAVmed Inc. (the “Company”) hereby requests acceleration of the effectiveness of the above-referenced Registration Statement (File No. 333-222581), so that such Registration Statement will become effective at 4:30 p.m. Eastern Time on Wednesday, May 23, 2018, or as soon thereafter as practicable.

Sincerely,
PAVMED INC.
By:	/s/ Lishan Aklog, M.D.
Name:	Lishan Aklog, M.D.
Title:	Chairman and Chief Executive Officer