Exhibit 107

Calculation of Filing Fee Tables

Form S-3

(Form Type)

COGENT BIOSCIENCES, INC.

(Exact Name of Registrant as Specified in its Charter)

Table 1: Newly Registered and Carry Forward Securities

Security   Type

Security     Class Title

Fee Calculation or Carry   Forward Rule

Amount Registered

Proposed   Maximum   Offering Price Per Unit

Maximum   Aggregate Offering Price

Fee   Rate

Amount of   Registration   Fee

Carry   Forward   Form Type

Carry   Forward   File Number

Carry Forward Initial   effective   date

Filing Fee Previously Paid In   Connection   with Unsold Securities to be Carried Forward

Newly Registered Securities

Equity

Common stock, $0.001 par value per share

Rule 456(b) and Rule 457(r) (2)

(2)

(2)

(2)

(1)

(1)

Equity

Preferred stock, $0.001 par value per share

Rule 456(b) and Rule 457(r) (2)

(2)

(2)

(2)

(1)

(1)

Debt

Debt securities

Rule 456(b) and Rule 457(r) (2)

(2)

(2)

(2)

(1)

(1)

Other

Warrants

Rule 456(b) and Rule 457(r)(2)

(2)

(2)

(2)

(1)

(1)

Other

Units (3)

Rule 456(b) and Rule 457(r) (2)

(2)

(2)

(2)

(1)

(1)

Fees Previously Paid

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Carry Forward Securities

Carry Forward Securities

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

N/A

Total Offering Amounts

N/A

N/A

Total Fees Previously Paid

N/A

Total Fee Offsets

N/A

Net Fee Due

N/A

(1) The registrant is deferring payment of the registration fee pursuant to Rule 456(b) under the Securities Act of 1933, as amended (the “Securities Act”) and is excluding this information in reliance on Rule 456(b) and Rule 457(r) under the Securities Act. Any additional registration fees will be paid subsequently on a pay-as-you-go basis.

(2) The registrant is registering hereby an indeterminate initial offering price and number or amount of securities of each identified class of securities as may from time to time be sold at indeterminate prices.

(3) Any securities registered hereunder may be sold separately or as units with other securities registered hereunder.