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Supplemental Financial Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Quarterly Financial Information Disclosure [Abstract]                      
Revenues $ 593 $ 2,361 $ 1,483 $ 437 $ 1,071 $ 1,169 $ 483 $ 1,726 $ 4,874 $ 4,449  
Operating expenses                      
Cost of product sales 4,702 8,231 7,185 4,681 6,272 6,453 4,600 5,436 24,799 22,761  
Research and development cost 315 282 338 620 857 967 1,203 1,475 1,555 4,502  
General and administrative expense 5,856 5,107 4,335 4,016 6,352 2,174 3,913 1,775 19,314 14,214 $ 600
Total operating expenses 10,873 13,620 11,858 9,317 13,481 9,594 9,716 8,686 45,668 41,477  
Loss from operations (10,280) (11,259) (10,375) (8,880) (12,410) (8,425) (9,233) (6,960) (40,794) (37,028)  
Other income and expense                      
Insurance proceeds net of related expenses (792) 0 0 0         (792) 0  
Interest expense (243) (142) (203) (2,889) (1,222) (919) (719) (587) (3,477) (3,447)  
Interest and other income 45 85 77 63 100 81 25 17 270 223  
Total other expense, net (990) (57) (126) (2,826) (1,122) (838) (694) (570) (3,999) (3,224)  
Loss before income tax expense (11,270) (11,316) (10,501) (11,706) (13,532) (9,263) (9,927) (7,530) (44,793) (40,252)  
Income tax expense 0 0 0 (2) 0 0 0 (2) (2) (2)  
Net loss $ (11,270) $ (11,316) $ (10,501) $ (11,708) $ (13,532) $ (9,263) $ (9,927) $ (7,532) $ (44,795) $ (40,254)  
Weighted average shares outstanding, basic and diluted (in shares) 57,523,283 57,053,982 50,757,448 43,514,225 38,905,282 38,779,710 30,134,995 27,768,008 52,263,885 34,154,826  
Basic and diluted net loss per share (in dollars per share) $ (0.20) $ (0.20) $ (0.21) $ (0.27) $ (0.35) $ (0.24) $ (0.33) $ (0.27) $ (0.86) $ (1.18)