Represents the total number of contracts with customers.

No definition available.

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- Definition

Amount of up-front payment received under terms of the agreement.

+ References

No definition available.

+ Details

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Data Type:	xbrli:monetaryItemType
Balance Type:	debit
Period Type:	duration

- Definition

Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable.

+ References

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Period Type:	instant

- Definition

Amount of revenue recognized that was previously included in balance of obligation to transfer good or service to customer for which consideration from customer has been received or is due.

+ References

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Balance Type:	credit
Period Type:	duration

- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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Namespace Prefix:	us-gaap_
Data Type:	xbrli:stringItemType
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- Definition

Amount of increase (decrease) in obligation to transfer good or service to customer for which consideration has been received or is receivable.

+ References

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- Definition

Amount, excluding tax collected from customer, of revenue from satisfaction of performance obligation by transferring promised good or service to customer. Tax collected from customer is tax assessed by governmental authority that is both imposed on and concurrent with specific revenue-producing transaction, including, but not limited to, sales, use, value added and excise.

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+ Details

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- Details

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Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

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Namespace Prefix:
Data Type:	na
Balance Type:
Period Type:

- Details

Name:	us-gaap_TypeOfArrangementAxis=us-gaap_CollaborativeArrangementMember
Namespace Prefix:
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Balance Type:
Period Type:

- Details

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Namespace Prefix:
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Period Type:

Revenue - Revenue from contracts with customers (Details)			1 Months Ended	12 Months Ended
	Jan. 01, 2021 USD ($)	Jan. 13, 2020 USD ($)	Oct. 31, 2021 USD ($)	Dec. 31, 2021 USD ($) contract	Dec. 31, 2020 USD ($)	Dec. 31, 2019 USD ($)
Revenue
Revenue				$ 6,149,000	$ 3,958,000	$ 1,122,000
Number of contracts with customers \| contract				3
Increase in deferred revenue	$ 147,330,000			$ 149,785,000	47,973,000	2,095,000
Deferred revenue	$ 52,092,000			199,422,000
Development revenue
Revenue
Revenue				6,149,000	3,958,000	$ 1,122,000
GSK Collaboration And License Agreement
Revenue
Upfront payment received			$ 150,000,000
Astellas Collaboration Agreement
Revenue
Upfront payment received		$ 50,000,000
Astellas Collaboration Agreement \| GlaxoSmithKline Intellectual Property Development Ltd
Revenue
Deferred revenue					$ 52,092,000
Revenue recognized in the period				$ 1,498,000