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Convertible Preferred Stock - Additional Information (Detail)
$ / shares in Units, $ in Thousands
1 Months Ended 6 Months Ended 12 Months Ended
May 24, 2018
USD ($)
Jan. 17, 2018
USD ($)
shares
Dec. 31, 2017
USD ($)
shares
Jul. 31, 2017
USD ($)
shares
Jul. 31, 2016
USD ($)
shares
Jun. 30, 2018
USD ($)
$ / shares
shares
Jun. 30, 2017
USD ($)
Dec. 31, 2017
USD ($)
Jan. 18, 2018
USD ($)
Temporary Equity [Line Items]                  
Cash dividends           $ 200      
Accrued and unpaid dividends     $ 5,200         $ 5,200  
Issuance costs $ 1,400         611 $ 648    
Loss on issuance of redeemable convertible preferred stock           $ 47,920 $ 0    
Number of shares of to purchase capital stock (in shares) | shares   11,875       2,000,000      
Stock option warrant to purchase, exercise price per share | $ / shares           $ 6.30      
Warrants fair value                 $ 14,100
Number of converted shares (in shares) | shares     80            
Series D Two Convertible Preferred Stock                  
Temporary Equity [Line Items]                  
Liquidation preference     $ 18,200         $ 18,200  
Common Stock                  
Temporary Equity [Line Items]                  
Number of converted shares (in shares) | shares   40,016,067              
Exchange of shares   1              
Consideration received   $ 20,000              
Number of converted shares (in shares) | shares   270,969,445              
Convertible Preferred Stock                  
Temporary Equity [Line Items]                  
Shares issued (in shares) | shares           0      
Shares outstanding (in shares) | shares           0      
Issuance and sale of an aggregate shares (in shares) | shares   5,000,000              
Series D                  
Temporary Equity [Line Items]                  
Shares issuable upon conversion, percentage of discount to the issuance price               50.00%  
Accrued dividend     $ 5,200         $ 5,200  
Loss on issuance of redeemable convertible preferred stock               35,200  
Percent of purchase price paid           (75.00%)      
Number of shares of Series D to purchase capital stock, value           $ 30,000      
Number of converted shares (in shares) | shares   80              
Series D excluding Series D 2X Liquidation Preference                  
Temporary Equity [Line Items]                  
Warrant maturity           7 years      
WIM | Series D                  
Temporary Equity [Line Items]                  
Issuance and sale of an aggregate shares (in shares) | shares       80          
Consideration received       $ 500          
Neothetics                  
Temporary Equity [Line Items]                  
Number of converted shares (in shares) | shares           41,273,941      
Neothetics | Common Stock                  
Temporary Equity [Line Items]                  
Number of converted shares (in shares) | shares           515,924      
Exchange of shares   0.1540       0.1540      
Shares exchanged (in shares) | shares   3              
Number of shares of to purchase capital stock (in shares) | shares           2,000,000      
Stock option warrant to purchase, exercise price per share | $ / shares           $ 8.35      
Neothetics | Series D                  
Temporary Equity [Line Items]                  
Number of converted shares (in shares) | shares   80              
Amended Cosmederm Note | Cosmederm                  
Temporary Equity [Line Items]                  
Number of converted shares (in shares) | shares         10        
Outstanding debt         $ 10,000        
Converted debt         5,000        
Canceled convertible debt         $ 5,000        
Cash | Series D                  
Temporary Equity [Line Items]                  
Proceeds, net of issuance costs               35,000  
Cosmederm Biosciences Inc | Series D                  
Temporary Equity [Line Items]                  
Issuance costs               300  
Cosmederm Biosciences Inc | Conversion Of Notes | Series D                  
Temporary Equity [Line Items]                  
Proceeds, net of issuance costs               5,000  
Cosmederm Biosciences Inc | Notes Payable To Related Party | Series D                  
Temporary Equity [Line Items]                  
Loss on extinguishment of related-party note payable               $ 6,700