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Income Taxes - Reconciliation of Federal Statutory Rate and Effective Tax Rate (Details)
12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Dec. 31, 2018
Income Tax Disclosure [Abstract]      
Tax expense at federal statutory rate (21.00%) (21.00%) (21.00%)
State income taxes, net of federal tax benefit (11.20%) (3.00%) (5.90%)
Share-based compensation (52.50%) (0.90%) (16.50%)
Section 162(m) of Internal Revenue Code 2.30% 1.10% 1.00%
Research and development credits (10.60%) (7.20%) (8.40%)
Meals and entertainment 0.50% 1.10% 1.80%
Return to provision adjustments (0.80%) 0.50% (4.20%)
Enactment of Tax Act 0.00% 0.00% (1.90%)
Other (0.20%) (0.60%) 0.40%
Valuation allowance 89.10% 28.60% 34.00%
Effective tax rate (4.40%) (1.40%) (20.70%)