Consolidated Schedule of Investments   (unaudited) March 31, 2021 BlackRock Science and Technology Trust (BST) (Percentages shown are based on Net Assets)

Security	Shares		Value
Common Stocks
Automobiles — 2.5%
Arrival Group, (Acquired 03/23/21, Cost: $6,054,719)(a)		835,013	$	12,762,137
Tesla, Inc.(b)(c)		28,792		19,231,041
				31,993,178
Diversified Consumer Services — 0.8%
Chegg, Inc.(b)(c)		120,357		10,309,781
Diversified Financial Services(a) — 0.6%
Linklogis, Inc., Class B, (Acquired 03/31/21, Cost: $2,624,480)		1,149,000		2,624,480
TransferWise, (Acquired 06/03/19, Cost: $2,471,478)(d)		27,945		5,181,282
				7,805,762
Electrical Equipment — 0.4%
Shoals Technologies Group, Inc., Class A(b)(c)		150,565		5,236,651
Electronic Equipment, Instruments & Components — 0.8%
Samsung SDI Co. Ltd.		18,473		10,862,530
Entertainment(b) — 3.1%
Activision Blizzard, Inc.		108,823		10,120,539
NetEase, Inc., ADR		77,307		7,982,721
Netflix, Inc.(c)		12,744		6,648,035
Roku, Inc.(c)		45,378		14,782,791
				39,534,086
Health Care Technology — 0.5%
Teladoc Health, Inc.(b)(c)		37,308		6,780,729
Hotels, Restaurants & Leisure — 0.3%
Airbnb, Inc., Class A(b)(c)		20,734		3,896,748
Interactive Media & Services — 10.7%
Alphabet, Inc., Class A(b)(c)		14,848		30,624,297
Baidu, Inc., ADR(c)		31,597		6,873,927
Facebook, Inc., Class A(b)(c)		59,113		17,410,552
Kakao Corp.		53,083		23,429,776
Snap, Inc., Class A(b)(c)		303,479		15,868,917
Tencent Holdings Ltd.		296,700		23,678,890
Yandex NV, Class A(b)(c)		162,287		10,396,105
ZoomInfo Technologies, Inc., Class A(b)(c)		208,111		10,176,628
				138,459,092
Internet & Direct Marketing Retail — 6.5%
Amazon.com, Inc.(b)(c)		10,322		31,937,094
Delivery Hero SE(c)(e)		88,059		11,413,959
Ensogo Ltd.(c)(d)		173,282		1
Jasper Infotech Private Ltd., Series I, (Acquired 08/18/15, Cost: $1,998,435)(a)(d)		1,054		251,031
JD Health International, Inc., (Acquired 12/01/20, Cost: $7,167,887)(a)		779,400		10,964,286
Meituan, Class B(c)(e)		304,696		11,890,514
MercadoLibre, Inc.(b)(c)		12,046		17,733,399
				84,190,284
IT Services — 18.9%
Adyen NV(c)(e)		4,997		11,150,326
Fiserv, Inc.(b)(c)		77,912		9,274,645
GMO Payment Gateway, Inc.		73,400		9,753,174
Klarna Holdings AB, (Acquired 08/07/19, Cost: $7,971,978)(a)(d)		26,430		30,740,655
Mastercard, Inc., Class A(b)		77,060		27,437,213
MongoDB, Inc.(b)(c)		29,473		7,881,964

Security	Shares		Value
IT Services (continued)
Okta, Inc.(b)(c)		65,447	$	14,426,482
Pagseguro Digital Ltd., Class A(b)(c)		150,560		6,970,928
PayPal Holdings, Inc.(b)(c)		103,291		25,083,187
Shopify, Inc., Class A(b)(c)		15,176		16,792,244
Snowflake, Inc., Class A(b)(c)		8,644		1,981,896
Square, Inc., Class A(b)(c)		116,038		26,346,428
StoneCo Ltd., Class A(b)(c)		158,853		9,724,981
Twilio, Inc., Class A(b)(c)		73,112		24,913,645
Visa, Inc., Class A(b)		101,893		21,573,805
				244,051,573
Road & Rail(b)(c) — 1.8%
Lyft, Inc., Class A		190,755		12,051,901
Uber Technologies, Inc.		195,775		10,671,695
				22,723,596
Semiconductors & Semiconductor Equipment — 15.2%
Advanced Micro Devices, Inc.(b)(c)		234,019		18,370,492
ASML Holding NV		38,607		23,688,067
Cree, Inc.(b)(c)		119,471		12,918,399
Inphi Corp.(b)(c)		89,383		15,946,821
Lam Research Corp.(b)		40,107		23,873,291
Marvell Technology Group Ltd.(b)		343,317		16,815,667
Monolithic Power Systems, Inc.(b)		34,560		12,206,938
Qualcomm, Inc.(b)		55,873		7,408,201
Renesas Electronics Corp.(c)		1,105,700		12,106,101
Skyworks Solutions, Inc.(b)		52,394		9,613,251
SOITEC SA(c)		73,604		15,024,661
STMicroelectronics NV		257,458		9,836,271
Taiwan Semiconductor Manufacturing Co. Ltd., ADR(b)		148,761		17,595,451
				195,403,611
Software — 19.8%
Adobe, Inc.(b)(c)		38,188		18,153,430
Atlassian Corp. PLC, Class A(b)(c)		46,274		9,752,708
Autodesk, Inc.(b)(c)		42,883		11,885,023
Avalara, Inc.(b)(c)		78,563		10,482,661
C3.AI, Inc., Class A, (Acquired 12/08/20, Cost: $5,703,600)(a)		188,667		12,200,158
C3.AI, Inc., Class A(b)(c)		75,452		4,973,041
Cadence Design Systems, Inc.(b)(c)		84,545		11,581,820
Coupa Software, Inc.(b)(c)		41,142		10,469,816
Crowdstrike Holdings, Inc., Class A(b)(c)		52,434		9,569,729
Databricks, Inc., (Acquired 07/24/20, Cost: $960,476)(a)(d)		19,999		3,180,841
Elastic NV(b)(c)		56,525		6,285,580
Intuit, Inc.(b)		27,360		10,480,522
Kingdee International Software Group Co. Ltd.		2,911,000		9,128,862
Microsoft Corp.(b)		192,615		45,412,839
Paycom Software, Inc.(b)(c)		21,310		7,885,979
RingCentral, Inc., Class A(b)(c)		37,761		11,248,247
salesforce.com, Inc.(b)(c)		49,566		10,501,548
ServiceNow, Inc.(b)(c)		29,527		14,766,748
Unity Software, Inc.(b)(c)		82,066		8,232,040
Xero Ltd.(c)		112,503		10,888,705
Zoom Video Communications, Inc., Class A(b)(c)		17,056		5,479,922
Zscaler, Inc.(b)(c)		72,711		12,482,297
				255,042,516

CONSOLIDATED SCHEDULE OF INVESTMENTS 1

Consolidated Schedule of Investments  (unaudited) (continued) March 31, 2021 BlackRock Science and Technology Trust (BST) (Percentages shown are based on Net Assets)

Security	Shares		Value
Specialty Retail — 0.6%
Auto1 Group SE(c)(e)		84,139	$	4,770,685
Cazoo Ltd., (Acquired 10/08/20, Cost: $1,414,228)(a)(d)		102,926		3,150,040
				7,920,725
Technology Hardware, Storage & Peripherals — 3.7%
Apple, Inc.(b)		390,361		47,682,596
Total Common Stocks — 86.2% (Cost: $350,388,435)				1,111,893,458
Preferred Securities
Preferred Stocks — 12.6%(a)(d)
Diversified Consumer Services — 0.5%
Think & Learn Private Ltd.
(Acquired 09/30/20, Cost: $1,524,948)		997		3,236,386
Series F, (Acquired 09/30/20, Cost: $3,052,975)		1,054		3,421,415
				6,657,801
Diversified Financial Services — 0.4%
TransferWise
Series A, (Acquired 06/03/19, Cost: $1,004,242)		11,355		2,105,330
Series B, (Acquired 06/03/19, Cost: $288,407)		3,261		604,622
Series C, (Acquired 06/03/19, Cost: $161,315)		1,824		338,188
Series D, (Acquired 06/03/19, Cost: $44,579)		504		93,447
Series E, (Acquired 06/03/19, Cost: $4,688)		53		9,827
TransferWise (Seed Preferred), (Acquired 06/03/19, Cost: $849,295)		9,603		1,780,492
				4,931,906
Electrical Equipment — 0.5%
Credo Technology Group Holding Ltd.
Series D, (Acquired 03/20/20, Cost: $5,000,001)		1,001,382		5,818,029
Series D+, (Acquired 01/22/20, Cost: $404,498)		69,679		404,835
				6,222,864
Food Products — 0.3%
Farmer’s Business Network, Inc., Series F, (Acquired 07/31/20, Cost: $2,999,887)		90,750		3,477,540
IT Services — 2.9%
Ant Group Co., Ltd, Series C, (Acquired 05/18/18, Cost: $6,492,863)		1,157,373		8,009,021
Automattic, Inc., Series E, (Acquired 02/03/21, Cost: $7,999,945)		94,117		7,999,945
Deep Instinct Ltd., Series D-2, (Acquired 03/19/21, Cost: $2,999,391)		493,493		2,999,391
TRAX Ltd.
Series D, (Acquired 02/18/21, Cost: $1,999,989)		38,361		2,030,064
Series E, (Acquired 09/12/19, Cost: $4,000,013)		106,667		5,644,818
Trumid Holdings LLC(f)
Class J-A, (Acquired 07/24/20, Cost: $2,499,716)		5,038		2,544,190
Class J-B, (Acquired 07/24/20, Cost: $1,499,830)		5,038		2,544,190
Xiaoju Kuaizhi, Inc., Series A-17, (Acquired 07/28/15, Cost: $3,016,964)		110,003		5,992,964
				37,764,583

Security	Shares		Value
Road & Rail — 0.2%
FlixMobility GmbH, Series F, (Acquired 07/26/19, Cost: $5,482,937)		275	$	3,089,156
Semiconductors & Semiconductor Equipment — 2.5%
Innovium, Inc.
Series E, (Acquired 08/21/19, Cost: $3,000,003)		353,478		3,428,737
Series F, (Acquired 06/10/20, Cost: $2,999,996)		296,062		3,209,312
Nuvia, Inc., Series B, (Acquired 09/17/20, Cost: $2,999,998)		935,352		7,707,300
Psiquantum Corp., Series C, (Acquired 09/09/19, Cost: $3,200,234)		690,003		3,249,914
SambaNova Systems, Inc., Series C, (Acquired 02/20/20, Cost: $9,972,126)		187,300		14,566,321
				32,161,584
Software — 3.7%
Avidxchange, Inc., (Acquired 07/29/20, Cost: $2,022,088)		41,257		2,229,941
Databricks, Inc.
Series F, (Acquired 10/22/19, Cost: $3,999,999)		93,135		14,813,122
Series G, (Acquired 02/01/21, Cost: $4,500,001)		25,371		4,035,258
DataRobot, Inc.
Series F, (Acquired 10/27/20, Cost: $2,999,996)		228,276		3,086,291
Series F, (Acquired 03/01/21, Cost: $583,275)		38,789		524,427
GitLab, Inc., Series E, (Acquired 09/10/19, Cost: $2,915,501)		156,500		6,349,205
Online Ventures Pty Ltd., Series C, (Acquired 01/21/20, Cost: $6,160,136)		53,642		7,317,176
Unqork, Inc.
Series B, (Acquired 09/19/19, Cost: $3,198,416)		7,027		7,695,830
Series C, (Acquired 09/18/20, Cost: $1,303,260)		1,190		1,303,264
				47,354,514
Specialty Retail — 0.7%
Cazoo Ltd.
Series A, (Acquired 10/08/20, Cost: $46,195)		3,362		102,894
Series B, (Acquired 10/08/20, Cost: $808,325)		58,829		1,800,456
Series C, (Acquired 10/08/20, Cost: $16,392)		1,193		36,511
Series D, (Acquired 10/08/20, Cost: $2,887,649)		210,160		6,431,926
				8,371,787
Technology Hardware, Storage & Peripherals — 0.9%
ByteDance Ltd., Series E-1, (Acquired 11/11/20, Cost: $9,999,959)		91,262		11,998,891
Total Preferred Stocks — 12.6%				162,030,626
Total Preferred Securities — 12.6%
(Cost: $114,940,032)				162,030,626
Warrants
IT Services — 0.0%
TRAX Ltd., (Acquired 09/12/19, Cost: $0)(a)(d)		17,065		134,984
Total Warrants — 0.0%
(Cost: $ — )				134,984
Total Long-Term Investments — 98.8% (Cost: $465,328,467)				1,274,059,068

2

Consolidated Schedule of Investments  (unaudited) (continued) March 31, 2021 BlackRock Science and Technology Trust (BST) (Percentages shown are based on Net Assets)

Security	Shares		Value
Short-Term Securities
Money Market Funds — 1.4%
BlackRock Liquidity Funds, T-Fund, Institutional Class, 0.01%(g)(h)		18,792,968	$	18,792,968
Total Short-Term Securities — 1.4%
(Cost: $18,792,968)				18,792,968
Total Investments Before Options Written — 100.2%
(Cost: $484,121,435)				1,292,852,036
Options Written — (0.6)%
(Premiums Received: $(14,215,964))				(7,841,645	)
Total Investments, Net of Options Written — 99.6% (Cost: $469,905,471)				1,285,010,391
Other Assets Less Liabilities — 0.4%				4,714,550
Net Assets — 100.0%			$	1,289,724,941

^(a)  Restricted security as to resale, excluding 144A securities. The Trust held restricted securities with a current value of $243,220,520, representing 18.86% of its net assets as of period end, and an original cost of $151,307,313.

^(b)  All or a portion of the security has been pledged and/or segregated as collateral in connection with outstanding exchange-traded options written.

^(c)  Non-income producing security.

^(d)  Security is valued using significant unobservable inputs and is classified as Level 3 in the fair value hierarchy.

^(e)  Security exempt from registration pursuant to Rule 144A under the Securities Act of 1933, as amended. These securities may be resold in transactions exempt from registration to qualified institutional investors.

^(f)  All or a portion of the security is held by a wholly-owned subsidiary.

^(g)  Affiliate of the Trust.

^(h)  Annualized 7-day yield as of period end.

For Trust compliance purposes, the Trust’s industry classifications refer to one or more of the industry sub-classifications used by one or more widely recognized market indexes or rating group indexes, and/or as defined by the investment adviser. These definitions may not apply for purposes of this report, which may combine such industry sub-classifications for reporting ease.

Affiliates

Investments in issuers considered to be affiliate(s) of the Trust during the period ended March 31, 2021 for purposes of Section 2(a)(3) of the Investment Company Act of 1940, as amended, were as follows:

Affiliated Issuer	Value at 12/31/20		Purchases at Cost			Proceeds from Sales		Net Realized Gain (Loss)		Change in Unrealized Appreciation (Depreciation)		Value at 03/31/21		Shares Held at 03/31/21		Income			Capital Gain Distributions from Underlying Funds
BlackRock Liquidity Funds, T-Fund, Institutional Class	$	9,266,737	$	9,526,231	(a)	$	—	$	—	$	—	$	18,792,968		18,792,968	$	896		$	—
SL Liquidity Series, LLC, Money Market Series		—		—			—		—		—		—		—		2,282	(b)		—
								$	—	$	—	$	18,792,968			$	3,178		$	—

^(a)  Represents net amount purchased (sold).

^(b)  All or a portion represents securities lending income earned from the reinvestment of cash collateral from loaned securities, net of fees and collateral investment expenses, and other payments to and from borrowers of securities.

Derivative Financial Instruments Outstanding as of Period End

Exchange-Traded Options Written

Description	Number of Contracts		Expiration Date		Exercise Price		Notional Amount (000)		Value
Call
Facebook, Inc., Class A		9		04/01/21	USD	280.00	USD	265	$	(13,545	)
Lyft, Inc., Class A		90		04/01/21	USD	62.00	USD	569		(13,455	)
MasterCard, Inc., Class A		30		04/01/21	USD	342.50	USD	1,068		(42,375	)
Okta, Inc.		47		04/01/21	USD	277.50	USD	1,036		(1,739	)
RingCentral, Inc., Class A		38		04/01/21	USD	415.00	USD	1,132		(1,900	)
Uber Technologies, Inc.		156		04/01/21	USD	64.50	USD	850		(156	)
Activision Blizzard, Inc.		77		04/09/21	USD	97.00	USD	716		(1,964	)
Adobe, Inc.		30		04/09/21	USD	500.00	USD	1,426		(3,690	)
Airbnb, Inc., Class A		33		04/09/21	USD	215.00	USD	620		(1,848	)
Alphabet, Inc., Class A		10		04/09/21	USD	2,120.00	USD	2,063		(10,100	)
Apple, Inc.		116		04/09/21	USD	132.00	USD	1,417		(754	)
Autodesk, Inc.		34		04/09/21	USD	297.50	USD	942		(1,258	)
Cree, Inc.		113		04/09/21	USD	125.00	USD	1,222		(56,500	)
Crowdstrike Holdings, Inc., Class A		40		04/09/21	USD	235.00	USD	730		(300	)
Intuit, Inc.		18		04/09/21	USD	400.00	USD	690		(2,340	)

CONSOLIDATED SCHEDULE OF INVESTMENTS 3

Consolidated Schedule of Investments  (unaudited) (continued)	BlackRock Science and Technology Trust (BST)
March 31, 2021

Exchange-Traded Options Written (continued)

Description	Number of Contracts		Expiration Date		Exercise Price		Notional Amount (000)		Value
Call (continued)
Lam Research Corp.		28		04/09/21	USD	592.50	USD	1,667	$	(51,100	)
Lyft, Inc., Class A		93		04/09/21	USD	62.00	USD	588		(23,157	)
Marvell Technology Group Ltd.		155		04/09/21	USD	52.00	USD	759		(4,573	)
MasterCard, Inc., Class A		39		04/09/21	USD	362.50	USD	1,389		(9,965	)
MercadoLibre, Inc.		23		04/09/21	USD	1,775.00	USD	3,386		(9,890	)
Microsoft Corp.		111		04/09/21	USD	240.00	USD	2,617		(18,870	)
MongoDB, Inc.		54		04/09/21	USD	407.50	USD	1,444		(16,740	)
Netflix, Inc.		15		04/09/21	USD	575.00	USD	863		(585	)
Okta, Inc.		48		04/09/21	USD	280.00	USD	1,058		(5,232	)
Roku, Inc.		20		04/09/21	USD	430.00	USD	652		(320	)
ServiceNow, Inc.		16		04/09/21	USD	535.00	USD	800		(1,880	)
Shopify, Inc., Class A		12		04/09/21	USD	1,270.00	USD	1,328		(1,620	)
Snap, Inc., Class A		15		04/09/21	USD	70.00	USD	78		(113	)
Snap, Inc., Class A		15		04/09/21	USD	69.50	USD	78		(210	)
Snap, Inc., Class A		35		04/09/21	USD	65.00	USD	183		(508	)
Square, Inc., Class A		113		04/09/21	USD	250.00	USD	2,566		(12,769	)
StoneCo. Ltd., Class A		85		04/09/21	USD	85.00	USD	520		(4,675	)
Tesla, Inc.		25		04/09/21	USD	775.00	USD	1,670		(4,538	)
Twilio, Inc., Class A		27		04/09/21	USD	425.00	USD	920		(540	)
Visa, Inc., Class A		37		04/09/21	USD	217.50	USD	783		(3,608	)
Yandex NV, Class A		41		04/09/21	USD	67.50	USD	263		(1,333	)
Yandex NV, Class A		52		04/09/21	USD	69.00	USD	333		(650	)
Zoom Video Communications, Inc., Class A		61		04/09/21	USD	415.00	USD	1,960		(1,525	)
Zscaler, Inc.		65		04/09/21	USD	215.00	USD	1,116		(6,825	)
Activision Blizzard, Inc.		130		04/16/21	USD	105.00	USD	1,209		(1,430	)
Adobe, Inc.		28		04/16/21	USD	495.00	USD	1,331		(10,710	)
Advanced Micro Devices, Inc.		160		04/16/21	USD	95.00	USD	1,256		(1,440	)
Alphabet, Inc., Class A		11		04/16/21	USD	2,120.00	USD	2,269		(19,085	)
Amazon.com, Inc.		6		04/16/21	USD	3,250.00	USD	1,856		(6,645	)
Apple, Inc.		95		04/16/21	USD	136.25	USD	1,160		(998	)
Avalara, Inc.		124		04/16/21	USD	180.00	USD	1,655		(2,480	)
C3.AI, Inc., Class A		50		04/16/21	USD	165.00	USD	330		(750	)
C3.AI, Inc., Class A		49		04/16/21	USD	105.00	USD	323		(1,470	)
Cadence Design Systems, Inc.		271		04/16/21	USD	150.00	USD	3,712		(10,162	)
Chegg, Inc.		212		04/16/21	USD	125.00	USD	1,816		(1,060	)
Coupa Software, Inc.		38		04/16/21	USD	370.00	USD	967		(5,320	)
Cree, Inc.		113		04/16/21	USD	125.00	USD	1,222		(7,063	)
Crowdstrike Holdings, Inc., Class A		41		04/16/21	USD	230.00	USD	748		(697	)
Elastic NV		98		04/16/21	USD	175.00	USD	1,090		(490	)
Facebook, Inc., Class A		20		04/16/21	USD	287.50	USD	589		(26,000	)
Fiserv, Inc.		91		04/16/21	USD	130.00	USD	1,083		(865	)
Inphi Corp.		151		04/16/21	USD	170.00	USD	2,694		(145,715	)
Intuit, Inc.		19		04/16/21	USD	400.00	USD	728		(5,795	)
Intuit, Inc.		37		04/16/21	USD	385.00	USD	1,417		(27,380	)
Lyft, Inc., Class A		94		04/16/21	USD	60.00	USD	594		(41,360	)
Marvell Technology Group Ltd.		155		04/16/21	USD	55.00	USD	759		(5,425	)
MasterCard, Inc., Class A		38		04/16/21	USD	360.00	USD	1,353		(20,520	)
Microsoft Corp.		42		04/16/21	USD	245.00	USD	990		(5,775	)
MongoDB, Inc.		12		04/16/21	USD	410.00	USD	321		(240	)
Netflix, Inc.		15		04/16/21	USD	530.00	USD	795		(14,250	)
Pagseguro Digital Ltd., Class A		145		04/16/21	USD	60.00	USD	671		(1,450	)
Paycom Software, Inc.		33		04/16/21	USD	420.00	USD	1,221		(2,723	)
PayPal Holdings, Inc.		144		04/16/21	USD	260.00	USD	3,497		(27,936	)
RingCentral, Inc., Class A		18		04/16/21	USD	410.00	USD	536		(810	)
Roku, Inc.		106		04/16/21	USD	485.00	USD	3,453		(2,650	)
ServiceNow, Inc.		42		04/16/21	USD	590.00	USD	2,100		(7,770	)
Shoals Technologies Group Inc., Class A		131		04/16/21	USD	45.00	USD	456		(3,930	)
Shoals Technologies Group Inc., Class A		132		04/16/21	USD	50.00	USD	459		(3,300	)
Shopify, Inc., Class A		9		04/16/21	USD	1,480.00	USD	996		(675	)
Snap, Inc., Class A		583		04/16/21	USD	65.00	USD	3,049		(24,486	)
Snowflake, Inc., Class A		30		04/16/21	USD	265.00	USD	688		(4,050	)
Square, Inc., Class A		114		04/16/21	USD	260.00	USD	2,588		(15,504	)

4

Consolidated Schedule of Investments (unaudited) (continued) March 31, 2021 BlackRock Science and Technology Trust (BST)

Exchange-Traded Options Written (continued)

Description	Number of Contracts		Expiration Date		Exercise Price		Notional Amount (000)		Value
Call (continued)
Teladoc Health, Inc.		49		04/16/21	USD	300.00	USD	891	$	(319	)
Tesla, Inc.		22		04/16/21	USD	830.00	USD	1,469		(3,927	)
Twilio, Inc., Class A		85		04/16/21	USD	450.00	USD	2,896		(2,253	)
Unity Software, Inc.		143		04/16/21	USD	144.00	USD	1,434		(115	)
ZoomInfo Technologies, Inc., Class A		406		04/16/21	USD	65.00	USD	1,985		(6,090	)
Zscaler, Inc.		66		04/16/21	USD	220.00	USD	1,133		(1,980	)
Advanced Micro Devices, Inc.		180		04/23/21	USD	85.00	USD	1,413		(16,110	)
Airbnb, Inc., Class A		22		04/23/21	USD	210.00	USD	413		(6,743	)
Alphabet, Inc., Class A		14		04/23/21	USD	2,085.00	USD	2,888		(55,860	)
Amazon.com, Inc.		16		04/23/21	USD	3,250.00	USD	4,951		(31,640	)
Apple, Inc.		78		04/23/21	USD	128.00	USD	953		(9,399	)
Atlassian Corp. PLC, Class A		73		04/23/21	USD	237.50	USD	1,539		(15,512	)
Autodesk, Inc.		46		04/23/21	USD	285.00	USD	1,275		(25,875	)
Crowdstrike Holdings, Inc., Class A		39		04/23/21	USD	240.00	USD	712		(1,931	)
Facebook, Inc., Class A		110		04/23/21	USD	285.00	USD	3,240		(174,075	)
Fiserv, Inc.		91		04/23/21	USD	132.00	USD	1,083		(1,775	)
Lyft, Inc., Class A		73		04/23/21	USD	66.00	USD	461		(13,468	)
MasterCard, Inc., Class A		40		04/23/21	USD	390.00	USD	1,424		(2,760	)
Microsoft Corp.		55		04/23/21	USD	247.50	USD	1,297		(7,673	)
NetEase, Inc., ADR		135		04/23/21	USD	111.00	USD	1,394		(17,887	)
Netflix, Inc.		14		04/23/21	USD	565.00	USD	791		(12,180	)
Okta, Inc.		17		04/23/21	USD	235.00	USD	375		(7,268	)
Qualcomm, Inc.		97		04/23/21	USD	135.00	USD	1,286		(28,227	)
RingCentral, Inc., Class A		53		04/23/21	USD	350.00	USD	1,579		(5,698	)
ServiceNow, Inc.		45		04/23/21	USD	515.00	USD	2,251		(52,200	)
Snap, Inc., Class A		41		04/23/21	USD	60.00	USD	214		(8,303	)
Snap, Inc., Class A		30		04/23/21	USD	63.50	USD	157		(4,005	)
Taiwan Semiconductor Manufacturing Co. Ltd., ADR		34		04/23/21	USD	123.00	USD	402		(9,146	)
Teladoc Health, Inc.		46		04/23/21	USD	212.50	USD	836		(7,521	)
Tesla, Inc.		13		04/23/21	USD	790.00	USD	868		(9,653	)
Twilio, Inc., Class A		27		04/23/21	USD	375.00	USD	920		(16,267	)
Uber Technologies, Inc.		117		04/23/21	USD	65.00	USD	638		(2,223	)
Visa, Inc., Class A		70		04/23/21	USD	220.00	USD	1,482		(12,495	)
Zscaler, Inc.		29		04/23/21	USD	210.00	USD	498		(3,089	)
Zscaler, Inc.		108		04/23/21	USD	200.00	USD	1,854		(16,956	)
Activision Blizzard, Inc.		95		04/30/21	USD	94.50	USD	884		(19,332	)
Adobe, Inc.		26		04/30/21	USD	480.00	USD	1,236		(35,685	)
Advanced Micro Devices, Inc.		123		04/30/21	USD	84.50	USD	966		(21,402	)
Airbnb, Inc., Class A		17		04/30/21	USD	200.00	USD	320		(11,772	)
Apple, Inc.		42		04/30/21	USD	133.00	USD	513		(3,402	)
Apple, Inc.		32		04/30/21	USD	126.00	USD	391		(8,960	)
Autodesk, Inc.		33		04/30/21	USD	287.50	USD	915		(20,130	)
Coupa Software, Inc.		66		04/30/21	USD	300.00	USD	1,680		(19,965	)
Crowdstrike Holdings, Inc., Class A		26		04/30/21	USD	210.00	USD	475		(5,759	)
Intuit, Inc.		21		04/30/21	USD	390.00	USD	804		(18,375	)
Lam Research Corp.		67		04/30/21	USD	580.00	USD	3,988		(261,132	)
Lyft, Inc., Class A		219		04/30/21	USD	75.00	USD	1,384		(11,935	)
Marvell Technology Group Ltd.		114		04/30/21	USD	60.00	USD	558		(3,021	)
Marvell Technology Group Ltd.		184		04/30/21	USD	50.00	USD	901		(35,236	)
MercadoLibre, Inc.		21		04/30/21	USD	1,710.00	USD	3,092		(15,750	)
Microsoft Corp.		88		04/30/21	USD	237.50	USD	2,075		(56,760	)
MongoDB, Inc.		13		04/30/21	USD	300.00	USD	348		(7,410	)
NetEase, Inc., ADR		135		04/30/21	USD	109.00	USD	1,394		(27,675	)
PayPal Holdings, Inc.		142		04/30/21	USD	262.50	USD	3,448		(57,155	)
RingCentral, Inc., Class A		29		04/30/21	USD	370.00	USD	864		(3,190	)
Roku, Inc.		11		04/30/21	USD	400.00	USD	358		(3,460	)
salesforce.com, Inc.		87		04/30/21	USD	220.00	USD	1,843		(30,015	)
Shopify, Inc., Class A		26		04/30/21	USD	1,200.00	USD	2,877		(72,670	)
Skyworks Solutions, Inc.		107		04/30/21	USD	187.50	USD	1,963		(73,027	)
Snap, Inc., Class A		165		04/30/21	USD	64.00	USD	863		(25,245	)
Square, Inc., Class A		205		04/30/21	USD	250.00	USD	4,655		(113,262	)
StoneCo. Ltd., Class A		152		04/30/21	USD	73.00	USD	931		(7,980	)

CONSOLIDATED SCHEDULE OF INVESTMENTS 5

Consolidated Schedule of Investments  (unaudited) (continued) March 31, 2021 BlackRock Science and Technology Trust (BST)

Exchange-Traded Options Written (continued)

Description	Number of Contracts		Expiration Date		Exercise Price		Notional Amount (000)		Value
Call (continued)
Taiwan Semiconductor Manufacturing Co. Ltd., ADR		277		04/30/21	USD	121.00	USD	3,276	$	(103,875	)
Teladoc Health, Inc.		22		04/30/21	USD	225.00	USD	400		(2,607	)
Tesla, Inc.		4		04/30/21	USD	810.00	USD	267		(3,710	)
Twilio, Inc., Class A		43		04/30/21	USD	405.00	USD	1,465		(17,522	)
Uber Technologies, Inc.		156		04/30/21	USD	63.50	USD	850		(7,722	)
Visa, Inc., Class A		51		04/30/21	USD	230.00	USD	1,080		(5,687	)
Yandex NV, Class A		245		04/30/21	USD	68.50	USD	1,570		(27,562	)
Zoom Video Communications, Inc., Class A		32		04/30/21	USD	380.00	USD	1,028		(9,200	)
Activision Blizzard, Inc.		78		05/07/21	USD	98.00	USD	725		(16,302	)
Adobe, Inc.		23		05/07/21	USD	500.00	USD	1,093		(17,250	)
Advanced Micro Devices, Inc.		356		05/07/21	USD	83.00	USD	2,795		(89,000	)
Amazon.Com, Inc.		9		05/07/21	USD	3,195.00	USD	2,785		(64,755	)
Apple, Inc.		95		05/07/21	USD	126.00	USD	1,160		(31,112	)
Atlassian Corp. PLC, Class A		84		05/07/21	USD	230.00	USD	1,770		(53,340	)
Autodesk, Inc.		37		05/07/21	USD	277.50	USD	1,025		(42,550	)
Cree, Inc.		93		05/07/21	USD	116.00	USD	1,006		(50,220	)
Crowdstrike Holdings, Inc., Class A		37		05/07/21	USD	197.50	USD	675		(22,292	)
Marvell Technology Group Ltd.		183		05/07/21	USD	50.00	USD	896		(39,802	)
Microsoft Corp.		52		05/07/21	USD	245.00	USD	1,226		(18,044	)
Skyworks Solutions, Inc.		76		05/07/21	USD	190.00	USD	1,394		(48,830	)
Snap, Inc., Class A		137		05/07/21	USD	55.00	USD	716		(53,430	)
Snap, Inc., Class A		41		05/07/21	USD	57.50	USD	214		(12,402	)
StoneCo. Ltd., Class A		80		05/07/21	USD	70.00	USD	490		(8,800	)
Taiwan Semiconductor Manufacturing Co. Ltd., ADR		22		05/07/21	USD	119.00	USD	260		(11,110	)
Tesla, Inc.		11		05/07/21	USD	700.00	USD	735		(46,117	)
Tesla, Inc.		21		05/07/21	USD	745.00	USD	1,403		(54,915	)
Twilio, Inc., Class A		30		05/07/21	USD	370.00	USD	1,022		(41,400	)
Visa, Inc., Class A		23		05/07/21	USD	215.00	USD	487		(12,995	)
Yandex NV, Class A		230		05/07/21	USD	68.00	USD	1,473		(64,400	)
Adobe, Inc.		26		05/21/21	USD	490.00	USD	1,236		(35,490	)
Alphabet, Inc., Class A		14		05/21/21	USD	2,050.00	USD	2,888		(134,540	)
Amazon.com, Inc.		4		05/21/21	USD	3,260.00	USD	1,238		(26,660	)
Apple, Inc.		92		05/21/21	USD	140.00	USD	1,124		(8,832	)
Apple, Inc.		210		05/21/21	USD	130.00	USD	2,565		(56,595	)
Atlassian Corp. PLC, Class A		4		05/21/21	USD	230.00	USD	84		(3,040	)
Avalara, Inc.		150		05/21/21	USD	150.00	USD	2,001		(67,500	)
Chegg, Inc.		209		05/21/21	USD	99.00	USD	1,790		(47,889	)
Coupa Software, Inc.		39		05/21/21	USD	280.00	USD	993		(34,905	)
Cree, Inc.		99		05/21/21	USD	120.00	USD	1,071		(49,500	)
Elastic NV		99		05/21/21	USD	135.00	USD	1,101		(16,582	)
Facebook, Inc., Class A		37		05/21/21	USD	290.00	USD	1,090		(69,097	)
Inphi Corp.		161		05/21/21	USD	170.00	USD	2,872		(197,225	)
Lam Research Corp.		38		05/21/21	USD	580.00	USD	2,262		(181,355	)
Marvell Technology Group Ltd.		410		05/21/21	USD	52.50	USD	2,008		(70,315	)
Microsoft Corp.		37		05/21/21	USD	250.00	USD	872		(13,042	)
MongoDB, Inc.		24		05/21/21	USD	380.00	USD	642		(4,080	)
Monolithic Power Systems, Inc.		118		05/21/21	USD	370.00	USD	4,168		(193,520	)
Okta, Inc.		108		05/21/21	USD	260.00	USD	2,381		(32,562	)
Pagseguro Digital Ltd., Class A		156		05/21/21	USD	57.50	USD	722		(8,580	)
Paycom Software, Inc.		41		05/21/21	USD	430.00	USD	1,517		(32,185	)
PayPal Holdings, Inc.		77		05/21/21	USD	250.00	USD	1,870		(86,625	)
Qualcomm, Inc.		98		05/21/21	USD	140.00	USD	1,299		(38,465	)
Roku, Inc.		21		05/21/21	USD	350.00	USD	684		(45,727	)
salesforce.com, Inc.		80		05/21/21	USD	220.00	USD	1,695		(43,800	)
Shoals Technologies Group Inc., Class A		263		05/21/21	USD	40.00	USD	915		(71,010	)
Shopify, Inc., Class A		11		05/21/21	USD	1,225.00	USD	1,217		(43,560	)
Shopify, Inc., Class A		25		05/21/21	USD	1,150.00	USD	2,766		(164,125	)
Taiwan Semiconductor Manufacturing Co. Ltd., ADR		175		05/21/21	USD	130.00	USD	2,070		(40,687	)
Teladoc Health, Inc.		13		05/21/21	USD	195.00	USD	236		(12,935	)
Tesla, Inc.		4		05/21/21	USD	830.00	USD	267		(6,090	)
Twilio, Inc., Class A		43		05/21/21	USD	400.00	USD	1,465		(45,472	)
Uber Technologies, Inc.,		156		05/21/21	USD	60.00	USD	850		(29,796	)

6

Schedule of Investments  (unaudited) (continued) March 31, 2021 BlackRock Science and Technology Trust (BST)

Exchange-Traded Options Written (continued)

Description	Number of Contracts		Expiration Date		Exercise Price		Notional Amount (000)		Value
Call (continued)
Unity Software, Inc.		140		05/21/21	USD	130.00	USD	1,404	$	(24,500)
Visa, Inc., Class A		22		05/21/21	USD	220.00	USD	466		(9,460)
ZoomInfo Technologies, Inc., Class A		346		05/21/21	USD	55.00	USD	1,692		(77,850)
									$	(5,352,434)

OTC Options Written

Description	Counterparty	Number of Contracts		Expiration Date		Exercise Price			Notional Amount (000)			Value
Call
Kakao Corp.	Morgan Stanley & Co. International PLC		2,000		04/07/21		USD	497,175.00		USD	999,064	$	(17,587)
Kingdee International Software Group Co. Ltd.	Morgan Stanley & Co. International PLC		799,000		04/07/21		HKD	33.11		HKD	19,479		(34)
SOITEC SA.	UBS AG		1,500		04/07/21		EUR	177.88		EUR	261		(3,617)
Adyen NV	UBS AG		1,800		04/13/21		EUR	2,059.20		EUR	3,425		(18,098)
SOITEC SA.	Barclays Bank PLC		7,800		04/13/21		EUR	178.09		EUR	1,358		(28,948)
GMO Payment Gateway, Inc.	JPMorgan Chase Bank N.A.		14,000		04/14/21		JPY	14,516.48		JPY	205,979		(71,483)
Xero Ltd.	UBS AG		18,300		04/14/21		AUD	121.24		AUD	2,332		(106,820)
STMicroelectronics NV	UBS AG		27,400		04/15/21		EUR	33.66		EUR	893		(18,197)
ASML Holding NV	Goldman Sachs International		12,700		04/20/21		EUR	456.15		EUR	6,645		(1,029,504)
Delivery Hero SE.	Morgan Stanley & Co. International PLC		25,400		04/20/21		EUR	112.38		EUR	2,807		(123,699)
Meituan, Class B	Morgan Stanley & Co. International PLC		88,000		04/20/21		HKD	334.13		HKD	26,697		(69,907)
SOITEC SA.	Morgan Stanley & Co. International PLC		8,400		04/20/21		EUR	170.47		EUR	1,462		(77,653)
GMO Payment Gateway, Inc.	Goldman Sachs International		11,700		04/27/21		JPY	14,223.03		JPY	172,140		(96,093)
STMicroelectronics NV	UBS AG		24,100		04/27/21		EUR	30.73		EUR	785		(68,321)
Tencent Holdings Ltd.	Goldman Sachs International		123,900		04/27/21		HKD	715.53		HKD	76,871		(25,548)
Renesas Electronics Corp.	Goldman Sachs International		214,200		04/28/21		JPY	1,224.74		JPY	259,676		(75,011)
Meituan, Class B	Morgan Stanley & Co. International PLC		95,000		04/29/21		HKD	355.59		HKD	28,821		(66,312)
SOITEC SA.	UBS AG		7,500		05/04/21		EUR	169.82		EUR	1,305		(86,078)
Xero Ltd.	UBS AG		21,000		05/04/21		AUD	122.82		AUD	2,676		(132,113)
Kakao Corp.	Morgan Stanley & Co. International PLC		8,000		05/06/21		USD	512,940.00		USD	3,996,255		(108,320)
Kingdee International Software Group Co. Ltd.	Citibank N.A.		416,000		05/06/21		HKD	28.71		HKD	10,142		(41,663)
Samsung SDI Co. Ltd.	Citibank N.A.		6,400		05/06/21		USD	667,185.16		USD	4,259,161		(189,956)
Delivery Hero SE.	Goldman Sachs International		5,500		05/14/21		EUR	113.47		EUR	608		(34,249)
												$	(2,489,211)

Fair Value Hierarchy as of Period End

Various inputs are used in determining the fair value of financial instruments. These inputs to valuation techniques are categorized into a fair value hierarchy consisting of three broad levels for financial reporting purposes as follows:

• Level 1 – Unadjusted price quotations in active markets/exchanges for identical assets or liabilities that the Trust has the ability to access;

• Level 2 – Other observable inputs (including, but not limited to, quoted prices for similar assets or liabilities in markets that are active, quoted prices for identical or similar assets or liabilities in markets that are not active, inputs other than quoted prices that are observable for the assets or liabilities (such as interest rates, yield curves, volatilities, prepayment speeds, loss severities, credit risks and default rates) or other market–corroborated inputs); and

• Level 3 – Unobservable inputs based on the best information available in the circumstances, to the extent observable inputs are not available (including the BlackRock Global Valuation Methodologies Committee’s (the “Global Valuation Committee’s”) assumptions used in determining the fair value of financial instruments).

The hierarchy gives the highest priority to unadjusted quoted prices in active markets for identical assets or liabilities (Level 1 measurements) and the lowest priority to unobservable inputs (Level 3 measurements). Accordingly, the degree of judgment exercised in determining fair value is greatest for instruments categorized in Level 3. The inputs used to measure fair value may fall into different levels of the fair value hierarchy. In such cases, for disclosure purposes, the fair value hierarchy classification is determined based on the lowest level input that is significant to the fair value measurement in its entirety. Investments classified within Level 3 have significant unobservable inputs used by the Global Valuation Committee in determining the price for Fair Valued Investments. Level 3 investments include equity or debt issued by privately held companies or funds. There may not be a secondary market, and/or there are a limited number of investors. The categorization of a value determined for financial instruments

CONSOLIDATED SCHEDULE OF INVESTMENTS 7

Schedule of Investments  (unaudited) (continued) March 31, 2021 BlackRock Science and Technology Trust (BST)

Fair Value Hierarchy as of Period End (continued)

is based on the pricing transparency of the financial instruments and is not necessarily an indication of the risks associated with investing in those securities. For information about the Trust’s policy regarding valuation of financial instruments, refer to its most recent financial statements.

The following table summarizes the Trust’s investments categorized in the fair value hierarchy. The breakdown of the Trust’s investments into major categories is disclosed in the Consolidated Schedule of Investments above.

	Level 1		Level 2		Level 3		Total
Assets
Investments
Long-Term Investments
Common Stocks
Automobiles	$	19,231,041	$	12,762,137	$	—	$	31,993,178
Diversified Consumer Services		10,309,781		—		—		10,309,781
Diversified Financial Services		—		2,624,480		5,181,282		7,805,762
Electrical Equipment		5,236,651		—		—		5,236,651
Electronic Equipment, Instruments & Components		—		10,862,530		—		10,862,530
Entertainment		39,534,086		—		—		39,534,086
Health Care Technology		6,780,729		—		—		6,780,729
Hotels, Restaurants & Leisure		3,896,748		—		—		3,896,748
Interactive Media & Services		91,350,426		47,108,666		—		138,459,092
Internet & Direct Marketing Retail		49,670,493		34,268,759		251,032		84,190,284
IT Services		192,407,418		20,903,500		30,740,655		244,051,573
Road & Rail		22,723,596		—		—		22,723,596
Semiconductors & Semiconductor Equipment		134,748,511		60,655,100		—		195,403,611
Software		219,643,950		32,217,725		3,180,841		255,042,516
Specialty Retail		4,770,685		—		3,150,040		7,920,725
Technology Hardware, Storage & Peripherals		47,682,596		—		—		47,682,596
Preferred Securities
Preferred Stocks		—		—		162,030,626		162,030,626
Warrants		—		—		134,984		134,984
Short-Term Securities
Money Market Funds		18,792,968		—		—		18,792,968
	$	866,779,679	$	221,402,897	$	204,669,460	$	1,292,852,036
Derivative Financial Instruments(a)
Liabilities
Equity Contracts	$	(5,304,430)	$	(2,537,215)	$	—	$	(7,841,645)

^(a)  Derivative financial instruments are futures contracts. Futures contracts are valued at the unrealized appreciation (depreciation) on the instrument.

A reconciliation of Level 3 financial instruments is presented when the Trust had a significant amount of Level 3 investments at the beginning and/or end of the period in relation to net assets. The following table is a reconciliation of Level 3 investments for which significant unobservable inputs were used in determining fair value:

	Common Stocks			Preferred Stocks			Warrants			Total
Assets
Opening balance, as of December 31, 2020	$	37,043,595		$	124,970,280		$	189,763		$	162,203,638
Transfers into Level 3		—			—			—			—
Transfers out of Level 3		—			—			—			—
Other(a)		(15,104,799	)		15,104,799			—			—
Accrued discounts/premiums		—			—			—			—
Net realized gain (loss)		—			57,119			—			57,119
Net change in unrealized appreciation (depreciation)(b)		20,565,054			9,870,546			(54,779	)		30,380,821
Purchases		—			18,082,601			—			18,082,601
Sales		—			(6,054,719	)		—			(6,054,719	)
Closing balance, as of March 31, 2021	$	42,503,850		$	162,030,626		$	134,984		$	204,669,460
Net change in unrealized appreciation (depreciation) on investments still held at March 31, 2021(b)	$	20,565,056		$	24,195,731		$	(54,779)		$	44,706,008

^(a) Certain Level 3 investments were re-classified between Common Stocks and Preferred Stocks.

^(b)  Any difference between net change in unrealized appreciation (depreciation) and net change in unrealized appreciation (depreciation) on investments still held at March 31, 2021 is generally due to investments no longer held or categorized as Level 3 at period end.

8

Schedule of Investments  (unaudited) (continued) March 31, 2021 BlackRock Science and Technology Trust (BST)

The following table summarizes the valuation approaches used and unobservable inputs utilized by the BlackRock Global Valuation Methodologies Committee (the “Global Valuation Committee”) to determine the value of certain of the Trust’s Level 3 financial instruments as of period end.

	Value		Valuation Approach		Unobservable Inputs	Range of Unobservable Inputs Utilized(a)		Weighted Average of Unobservable Inputs
Assets
Common Stocks(b)	$	42,503,850		Market	Revenue Multiple		6.25x - 42.00x		23.32x
					Recent Transactions		–		–
Preferred Stocks(c)(d)		162,030,626		Income	Discount Rate		17% - 27%		23%
					Exit Multiple		8.75x		–
				Market	Revenue Multiple		2.65x - 42.00x		15.99x
					EBITDA Multiple		19.75x		–
					Volatility		41% - 58%		53%
					Time to Exit		2.5 - 5.0		3.0
					Recent Transactions		–		–
Warrants		134,984		Market	Recent Transactions		–		–
	$204,669,460

^(a)  A significant change in unobservable input would have resulted in a correlated (inverse) significant change to value.

^(b)  For the period end March 31, 2021, the valuation technique for investments classified as Common Stocks amounting to $3,150,040 changed to Transaction Price approach. The investments were previously valued utilizing Current Value Method. The change was due to consideration of the information that was available at the time the investments were valued.

^(c)  For the period end March 31, 2021, the valuation technique for investments classified as Preferred Stocks amounting to $23,456,969 changed to Current Value Method. The investments were previously valued utilizing Transaction Price Approach. The change was due to consideration of the information that was available at the time the investments were valued.

^(d)  For the period end March 31, 2021, the valuation technique for investments classified as Preferred Stocks amounting to $14,087,474 changed to Transaction Price approach. The investments were previously valued utilizing Current Value Method. The change was due to consideration of the information that was available at the time the investments were valued.

Currency Abbreviation

AUD	Australian Dollar
EUR	Euro
HKD	Hong Kong Dollar
JPY	Japanese Yen
USD	United States Dollar

Portfolio Abbreviation

ADR American Depositary Receipt

CONSOLIDATED SCHEDULE OF INVESTMENTS 9