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Stock-Based Compensation (Details)
1 Months Ended 3 Months Ended
Feb. 29, 2016
shares
Dec. 31, 2015
Mar. 31, 2024
item
shares
Jan. 30, 2023
shares
May 30, 2019
shares
2015 Equity Incentive Plan          
Stock-based compensation          
Expiration period   10 years      
Automatic annual increase in shares authorized, percent of common stock outstanding     3.50%    
Shares available for grant     46,186,700    
Inducement Plan          
Stock-based compensation          
Total shares that may be issued         1,800,000
Shares available for grant     282,159    
Commercial Equity Plan          
Stock-based compensation          
Total shares that may be issued       10,000,000  
Shares available for grant     7,675,000    
2016 Employee Stock Purchase Plan          
Stock-based compensation          
Total shares that may be issued 800,000   22,729,158    
Automatic annual increase in shares authorized, percent of common stock outstanding 1.00%        
Stock issued     199,066    
Payroll deductions for ESPP participants (as a percent)     15.00%    
Percentage on share price issued     85.00%    
Offering period duration     6 months    
Purchase periods | item     2    
1997 Stock Option Plan          
Stock-based compensation          
Total shares that may be issued     1,025,844