0001104659-23-060779.txt : 20230515 0001104659-23-060779.hdr.sgml : 20230515 20230515161526 ACCESSION NUMBER: 0001104659-23-060779 CONFORMED SUBMISSION TYPE: 13F-HR/A PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20220630 FILED AS OF DATE: 20230515 DATE AS OF CHANGE: 20230515 EFFECTIVENESS DATE: 20230515 FILER: COMPANY DATA: COMPANY CONFORMED NAME: VR Adviser, LLC CENTRAL INDEX KEY: 0001615982 IRS NUMBER: 464814731 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR/A SEC ACT: 1934 Act SEC FILE NUMBER: 028-20281 FILM NUMBER: 23922513 BUSINESS ADDRESS: STREET 1: 7 BRYANT PARK STREET 2: 23RD FLOOR CITY: NEW YORK STATE: NY ZIP: 10018 BUSINESS PHONE: 650-475-3734 MAIL ADDRESS: STREET 1: 7 BRYANT PARK STREET 2: 23RD FLOOR CITY: NEW YORK STATE: NY ZIP: 10018 13F-HR/A 1 primary_doc.xml X0202 13F-HR/A LIVE false false false 0001615982 XXXXXXXX 06-30-2022 06-30-2022 true 1 RESTATEMENT false VR Adviser, LLC

7 Bryant Park 23rd Floor New York NY 10018

13F HOLDINGS REPORT 028-20281 Y Note: VR Adviser, LLC is filing this Form 13F on behalf of itself and the general partner entities of the investment funds for which it serves as the investment adviser, VHCP Management II, LLC, VHCP Management III, LLC and VHCP Management EG, LLC. Note: This amendment is being filed solely to remove holdings of securities of DBV Technologies S A ("DBV") from the reporting manager's holdings of 13(f) securities as of June 30, 2022. The reporting manager's holdings of DBV equity securities as of June 30, 2022 consisted of ordinary shares, which are not considered "Section 13(f) securities" and are, therefore, not reportable on Form 13F, in contrast to American depositary shares, which are reportable on Form 13F. This amendment does not reflect the disposition of any securities of DBV by the reporting manager, but merely reflects the fact that the holdings as of June 30, 2022 were in the form of ordinary shares. As of June 30, 2022, the reporting manager's holdings included 9,300,000 ordinary shares of DBV. Sherman G. Souther 650-561-9580 /s/ Sherman G. Souther Palo Alto CA 05-15-2023 0 27 507777000 INFORMATION TABLE 2 infotable.xml Aadi Bioscience Inc COM 00032Q104 14458000 1173518 SH SOLE 1173518 0 0 Aclaris Therapeutics Inc COM 00461U105 63713000 4563962 SH SOLE 4563962 0 0 Aerovate Therapeutics Inc COM 008064107 9228000 590408 SH SOLE 590408 0 0 Affimed NV COM N01045108 3957000 1428571 SH SOLE 1428571 0 0 Akouos Inc COM 00973J101 12509000 2667119 SH SOLE 2667119 0 0 Altimmune Inc COM 02155H200 4321000 369306 SH SOLE 369306 0 0 Annexon Inc COM 03589W102 7270000 1928477 SH SOLE 1928477 0 0 aTyr Pharma Inc COM 002120202 3959000 1398889 SH SOLE 1398889 0 0 Celldex Therapeutics Inc COM 15117B202 23324000 865116 SH SOLE 865116 0 0 Chinook Therapeutics Inc COM 16961L106 8563000 489618 SH SOLE 489618 0 0 Cogent Biosciences Inc COM 19240Q201 36424000 4038117 SH SOLE 4038117 0 0 GH Research PLC ORD SH G3855L106 31792000 3185573 SH SOLE 3185573 0 0 Inozyme Pharma Inc COM 45790W108 12927000 2709987 SH SOLE 2709987 0 0 Instil Bio Inc COM 45783C101 27709000 5997657 SH SOLE 5997657 0 0 LianBio SPONS ADR 53000N108 11617000 5378341 SH SOLE 5378341 0 0 Lyra Therapeutics Inc COM 55234L105 5222000 924170 SH SOLE 924170 0 0 Marinus Pharmaceuticals Inc COM 56854Q200 15279000 3156803 SH SOLE 3156803 0 0 Provention Bio Inc COM 74374N102 4475000 1118653 SH SOLE 1118653 0 0 Rallybio Corp COM 75120L100 2027000 268532 SH SOLE 268532 0 0 Relmada Therapeutics Inc COM 75955J402 43109000 2270072 SH SOLE 2270072 0 0 Savara Inc COM 805111101 6259000 4117530 SH SOLE 4117530 0 0 Travere Therapeutics Inc COM 89422G107 41460000 1711102 SH SOLE 1711102 0 0 Trevi Therapeutics Inc COM 89532M101 8571000 3050022 SH SOLE 3050022 0 0 Tricida Inc COM 89610F101 69039000 7132079 SH SOLE 7132079 0 0 Viridian Therapeutics Inc COM 92790C104 21438000 1852919 SH SOLE 1852919 0 0 VistaGen Therapeutics Inc COM 92840H202 18214000 20697286 SH SOLE 20697286 0 0 Xenon Pharmaceuticals Inc COM 98420N105 913000 30000 SH SOLE 30000 0 0