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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
SAGE THERAPEUTICS, INC. COM 78667J108 3,579 37,362 SH   DFND 1,2,3 37,362 0 0
JOUNCE THERAPEUTICS, INC. COM 481116101 34,476 10,230,349 SH   DFND 1,2,3 10,230,349 0 0
BLUEPRINT MEDICINES CORPORATION COM 09627Y109 47,380 878,875 SH   DFND 1,2,3 878,875 0 0
ALLENA PHARMACEUTICALS, INC. COM 018119107 15,211 2,790,964 SH   DFND 1,2,3 2,790,964 0 0