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Shareholders' equity (Tables)
 9 Months Ended
Sep. 30, 2022
Stockholders' Equity Note [Abstract]  
Schedule of Nonvested Share Activity
The changes in number of outstanding prefunded warrants are as follows:
 
    
Prefunded
warrants
  
Balance as of December 31, 2021
   
 
—  
 
Granted during the period
      28,276,331  
Forfeited during the period
      —    
Exercised/released during the period
      —    
Expired during the period
      —    
    
 
 
  
Balance as of September 30, 2022
   
 
28,276,331