Exhibit 5.1

Date	8 December 2023
Our Ref	01413513

Medtronic plc

20 On Hatch

Lower Hatch Street

Dublin 2

Ireland

Medtronic plc (the Company)

Dear Sirs

We act as Irish counsel for the Company, a public limited company incorporated under the laws of Ireland (with registration number 545333), in connection with the proposed registration by the Company of 30,000,000 ordinary shares of the Company, nominal value $0.0001 per share (the Ordinary Shares), issuable under the 2024 Employee Stock Purchase Plan (the Plan) pursuant to a Registration Statement on Form S-8 (the Registration Statement) to be filed by the Company with the U.S. Securities and Exchange Commission (the SEC) under the Securities Act of 1933, as amended (the Securities Act).

In connection with this Opinion, we have reviewed copies of such corporate records of the Company as we have deemed necessary as a basis for the opinion hereinafter expressed. In rendering this Opinion, we have examined and have assumed the truth and accuracy of the contents of such documents and certificates of officers of the Company and of public officials as to factual matters and have conducted such searches, as of 8 December 2023, in public registries in Ireland as we have deemed necessary or appropriate for the purposes of this Opinion but have made no independent investigation regarding such factual matters. In our examination we have assumed the truth and accuracy of the information contained in such documents, the genuineness of all the signatures, authenticity of all documents submitted to us as originals, the conformity to original documents of all documents submitted to us as certified or photostatic copies and the authenticity of the originals of such documents.

We have further assumed:

1that, as of today's date and at each time Ordinary Shares are issued, none of the resolutions and authorities of the shareholders or directors of the Company upon which we have relied have been varied, amended or revoked in any respect or have expired and that the Ordinary Shares will be issued in accordance with such resolutions and authorities;

2that at each time Ordinary Shares will be issued, the Company will then have sufficient authorised but unissued share capital to allow for the issue of such Ordinary Shares and that the Ordinary Shares will be issued in accordance with the Plan;

3that any issue of Ordinary Shares pursuant to the Plan will be paid up in consideration of the receipt by the Company prior to, or simultaneously with, the issue of the Ordinary Shares of cash at least equal to the nominal value of such Ordinary Shares and that where such Ordinary Shares are issued under the Plan without the requirement for the payment of cash consideration by or on behalf of the relevant beneficiary, then such Ordinary Shares shall either be fully paid up by the Company or one of its subsidiaries within the time permitted by Section 1027 of the Companies Act 2014 of Ireland (the Act) (and, in the case of the Company or a subsidiary incorporated in Ireland, in a manner permitted by Section 82(6) and 1043 of the Act) or issued for consideration as set out in Section 1028(2) of the Act;

4that the filing of the Registration Statement with the SEC has been authorised by all necessary actions under all applicable laws other than Irish law;

5that when filed with the SEC, the Registration Statement will not differ in any material respect from the drafts that we have examined;

6that at the time of the grant by the board of directors of the Company (the Board), any committee of the Board, or any other duly authorized representative of the Company of an award or other allotment and issue of Ordinary Shares under the Plan, (i) the Board will be duly constituted and remain duly constituted; or (ii) that such committee will be duly constituted and will remain a duly constituted committee of the Board having the necessary powers and authorities to grant awards and issue the Ordinary Shares; or (iii) in the case of an authorised representative, that such person has the necessary powers and authorities to grant awards and issue the Ordinary Shares; and

7the absence of fraud on the part of the Company and its respective officers, employees, agents and advisors.

Having made such further investigation and reviewed such other documents as we have considered requisite or desirable, subject to the foregoing and to the within qualifications and assumptions, and provided that the Registration Statement, as finally amended, has become effective, we are of the opinion that;

1the Ordinary Shares have been duly authorised and when issued in accordance with the terms of the Plan and against valid payment therefor, and when the Registration Statement has become effective under the Securities Act, will be validly issued, fully paid and not subject to calls for any additional payments (“non-assessable”) (except for Ordinary Shares issued pursuant to deferred payment arrangements, which shall be fully paid upon the satisfaction of such payment obligations); and

2the obligations of the Company under the Plan have been duly authorised by all necessary corporate action on behalf of the Company.

In rendering this Opinion we have confined ourselves to matters of Irish law. We express no opinion on any laws other than the laws of Ireland (and the interpretation thereof) in force as at the date hereof. This Opinion speaks only as of its date. We are not under any obligation to update this Opinion from time to time, nor to notify you of any change of law, facts or circumstances referred to or relied upon in the giving of this Opinion.

This Opinion is given solely for the benefit of the addressee of this Opinion and may not be relied upon by any other person without our prior written consent, provided however, that it may be relied upon by persons entitled to rely on it pursuant to applicable provisions of U.S. federal securities laws.

This Opinion is also strictly confined to the matters expressly stated herein and is not to be read as extending by implication or otherwise to any other matter.

We hereby consent to the filing of this Opinion with the SEC as an exhibit to the Registration Statement.

This Opinion is governed by and construed in accordance with the laws of Ireland.

Yours faithfully

/s/ A & L Goodbody LLP