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Collaboration Revenue - Changes in Contract Asset Included in Prepaid Expenses and Other Current Assets, and Contract Liabilities (Detail) - ASU 2014-09 [Member] - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]        
Contract assets, Balance at Beginning of Period     $ 510 $ 306
Contract assets, Additions     175  
Contract assets, Deductions     (510) (8)
Contract assets, Balance at End of Period $ 175 $ 298 175 298
Contract liabilities:        
Balance at Beginning of Period     123,783 108,814
Additions     175  
Deductions (4,271) (3,014) (8,037) (6,029)
Balance at End of Period $ 115,921 $ 102,785 $ 115,921 $ 102,785