Property and Equipment, Net - Schedule of Property and Equipment, Net (Detail) - USD ($) $ in Thousands	Jun. 30, 2023	Dec. 31, 2022
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 71,993	$ 68,025
Less: Accumulated depreciation and amortization	(47,967)	(45,040)
Property and equipment, net	24,026	22,985
Laboratory Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	28,053	24,533
Computer Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	4,134	3,557
Furniture and Office Equipment [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	4,911	3,491
Leasehold Improvements [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	32,963	32,474
Construction in Progress [Member]
Property, Plant and Equipment [Line Items]
Property and equipment, gross	$ 1,932	$ 3,970