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Convertible Notes Payable - Schedule of Convertible Notes Payable (Detail) - USD ($)
Mar. 31, 2017
Dec. 31, 2016
Debt Instrument [Line Items]    
Conversion payoff value   $ 1,990,032
Discount on notes payable, current $ 0 (675,589)
Convertible notes payable, current (net of discount)   3,269,582
Conversion payoff value 2,002,252  
Discount on notes payable, long-term (244,362) 0
Convertible notes payable, long-term (net of discount) 3,713,029  
Ligand Note [Member] | Short Term Debt [Member]    
Debt Instrument [Line Items]    
Convertible note payable issued during 2014 to Ligand pursuant to the Master License Agreement with a 5% annual interest rate, due during 2016 (amended in January 2016 to a 2.5% annual interest rate with maturity extended to 2017, and subsequently amended in May 2017 with maturity extended to May 21, 2018)   $ 1,955,139
Ligand Note [Member] | Long Term Debt [Member]    
Debt Instrument [Line Items]    
Convertible note payable issued during 2014 to Ligand pursuant to the Master License Agreement with a 5% annual interest rate, due during 2016 (amended in January 2016 to a 2.5% annual interest rate with maturity extended to 2017, and subsequently amended in May 2017 with maturity extended to May 21, 2018) $ 1,955,139