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Stock-Based Compensation - Summary of Stock Option Activity (Detail)
9 Months Ended
Sep. 30, 2016
$ / shares
shares
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract]  
Options outstanding beginning balance, Shares Subject to Stock Options | shares 365,394
Granted, Shares Subject to Stock Options | shares 520,818
Cancelled, Shares Subject to Stock Options | shares (50,250)
Options outstanding ending balance, Shares Subject to Stock Options | shares 835,962
Options exercisable, Shares Subject to Stock Options | shares 291,824
Options outstanding beginning balance, Weighted-Average Exercise Price | $ / shares $ 8.48
Granted, Weighted-Average Exercise Price | $ / shares 2.17
Cancelled, Weighted-Average Exercise Price | $ / shares 4.34
Options outstanding ending balance, Weighted-Average Exercise Price | $ / shares 4.80
Options exercisable, Weighted-Average Exercise Price | $ / shares $ 6.30
Options outstanding, Weighted-Average Remaining Contractual Term 8 years 11 months 12 days
Options exercisable, Weighted-Average Remaining Contractual Term 8 years 5 months 16 days