Exhibit 107

CALCULATION OF FILING FEE TABLE

FORM S-8

(Form Type)

SCPHARMACEUTICALS INC.

(Exact Name of Registrant as Specified in its Charter)

Table I: Newly Registered Securities

Plan	Security Type	Security Class Title	Fee Calculation Rule	Amount Registered(1)	Proposed Maximum Offering Price Per Unit	Maximum Aggregate Offering Price	Fee Rate	Amount of Registration Fee
2017 Stock Option and Incentive Plan	Equity	Common Stock, par value $0.0001 per share	Rule 457(c) and 457(h)	1,370,316(2)	$6.80(4)	$9,318,148.80	$110.20 per million dollars	$1,026.86
2017 Employee Stock Purchase Plan	Equity	Common Stock, par value $0.0001 per share	Rule 457(c) and 457(h)	205,000(3)	$5.78(5)	$1,184,900.00	$110.20 per million dollars	$130.58
	Total Offering Amounts					$10,503,048.80		$1,157.44
	Total Fee Offsets							$—
	Net Fee Due							$1,157.44

(1) In accordance with Rule 416(a) under the Securities Act of 1933, as amended (“Securities Act”), this registration statement shall be deemed to cover any additional securities that may from time to time be offered or issued under the scPharmaceuticals Inc. 2017 Stock Option and Incentive Plan (the “Incentive Plan”) and the scPharmaceuticals Inc. 2017 Employee Stock Purchase Plan (the “ESPP”) to prevent dilution resulting from stock splits, stock dividends or similar transactions. In addition, pursuant to Rule 416(c) under the Securities Act, this registration statement also covers an indeterminate amount of interests to be offered or sold pursuant to the Incentive Plan and the ESPP.

(2) Consists of 1,370,316 shares of Common Stock that may become issuable under the Incentive Plan pursuant to its terms.

(3) Consists of 205,000 shares of Common Stock that may become issuable under the ESPP pursuant to its terms.

(4) Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act of 1933, as amended, and based upon the average of the high and low prices of the Common Stock as reported on the Nasdaq Global Select Market on March 15, 2023.

(5) Estimated solely for the purpose of calculating the registration fee pursuant to Rules 457(c) and 457(h) of the Securities Act of 1933, as amended, and based upon 85% of the average of the high and low prices of the Common Stock as reported on the Nasdaq Global Select Market on March 15, 2023. Pursuant to the ESPP, the purchase price of the shares of Common Stock reserved for issuance thereunder will be 85% of the fair market value of a share of Common Stock on the first trading day of the offering period or on the exercise date, whichever is less.