Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2023	Jun. 30, 2022
Operating activities
Net loss	$ (145,879)	$ (69,639)
Adjustments to reconcile net loss to net cash used in operating activities:
Gain on sale of ATOM Facility	0	(50,237)
Stock-based compensation expense	24,316	28,452
Depreciation and amortization expense	2,415	3,029
Accretion of liability related to sale of future revenues	2,456	0
Amortization (accretion) of investment premiums (discounts)	(1,106)	811
Non-cash operating lease expense	5,827	3,355
Other non-cash items, net	100	46
Changes in operating assets and liabilities:
Accounts receivable	39,714	349
Inventories	(6,275)	0
Prepaid expenses and other current assets	169	(1,546)
Other assets	(110)	76
Accounts payable	(2,780)	(3,384)
Accrued compensation	(5,103)	(8,833)
Accrued research and development expenses	(4,255)	1,674
Other current liabilities	3,685	2,891
Deferred revenue	2,514	(51,468)
Operating lease liabilities	(7,021)	(4,211)
Other long-term liabilities	108	142
Net cash used in operating activities	(91,225)	(148,493)
Investing activities
Purchases of short-term investments	(83,647)	(165,090)
Proceeds from maturities and sales of short-term investments	128,020	166,390
Purchases of property and equipment	(898)	(4,024)
Net proceeds from sale of ATOM Facility	0	94,765
Net cash (used in) provided by investing activities	43,475	92,041
Financing activities
Proceeds from issuance of common stock through ATM facilities, net	590	20,516
Proceeds from employee stock awards	747	1,405
Taxes paid related to net share settlement of restricted stock units	(94)	(619)
Principal payments on finance lease obligations	(524)	(190)
Other financing activities, net	(13)	(104)
Net cash provided by financing activities	706	21,008
Decrease in cash, cash equivalents and restricted cash	(47,044)	(35,444)
Cash, cash equivalents and restricted cash at beginning of period	93,088	107,478
Cash, cash equivalents and restricted cash at end of period	46,044	72,034
Non-cash investing and financing activities
Property and equipment purchases included in accounts payable and other accrued liabilities	108	132
Supplemental cash flow disclosure
Cash paid for interest	218	133
Cash paid for income taxes	$ 2	$ 19