Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2023	Mar. 31, 2022
Income Statement [Abstract]
Commercialization revenue	$ 884	$ 0
License and collaboration revenue	342	7,314
Total revenue	1,226	7,314
Costs and operating expenses:
Cost of commercialization revenue	216	0
Research and development expenses	62,156	74,963
General and administrative expenses	13,872	20,571
Total costs and operating expenses	76,244	95,534
Loss from operations	(75,018)	(88,220)
Other income (expense), net:
Interest income	1,802	228
Interest expense	(1,336)	(4)
Other income (expense), net	(197)	(109)
Total other income (expense), net	269	115
Loss before provision for income taxes	(74,749)	(88,105)
Provision for income taxes	22	0
Net loss	(74,771)	(88,105)
Other comprehensive gain (loss):
Unrealized gain (loss) on available-for-sale securities	830	(1,524)
Comprehensive loss	$ (73,941)	$ (89,629)
Basic loss per common share	$ (0.72)	$ (0.87)
Diluted loss per common share	$ (0.72)	$ (0.87)
Basic weighted-average shares outstanding	103,969	100,726
Diluted weighted-average shares outstanding	103,969	100,726