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Stockholders' Equity - Additional Information (Detail) - USD ($)
$ / shares in Units, $ in Millions
1 Months Ended 6 Months Ended
Apr. 25, 2022
Nov. 30, 2021
Jun. 30, 2022
Dec. 31, 2021
Dec. 31, 2020
Nov. 30, 2020
Jun. 30, 2020
Jul. 31, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Authorized capital stock     520,000,000          
Common stock, par value     $ 0.0001 $ 0.0001        
Common stock, shares authorized     500,000,000 500,000,000        
Preferred stock, par value     $ 0.0001          
Preferred stock, shares authorized     20,000,000          
Preferred stock, shares outstanding     0 0        
Stock option granted description terms     the exercise price of an option granted to a 10% shareholder cannot be less than 110% of the estimated fair value of the shares on the date of grant. Options granted generally vest over four years and expire in seven to ten years.          
Ownership percent     10.00%          
Shares of common stock, reserved for issuance     25,920,624          
2014 Equity Incentive Plan                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Shares of common stock, reserved for issuance     19,762,888          
Outstanding options and RSUs     15,589,015          
Aggregate number of awards available for grant to be issued     4,173,873          
Inducement Plan                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Shares of common stock, reserved for issuance     5,367,281          
Outstanding options and RSUs     3,742,764          
Aggregate number of awards available for grant to be issued     1,624,517          
Additional shares of common stock, reserved for issuance           1,500,000    
Restricted Stock Units (RSUs)                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Unrecognized stock-based compensation expense     $ 87.9          
Unrecognized stock-based compensation weighted average recognition period     3 years 1 month 6 days          
Restricted Stock Units (RSUs) | From Date Of Grant                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Share based compensation, vesting period     4 years          
Employees And Non Employees                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Share based compensation, vesting period     4 years          
Vested and Unvested Options                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Unrecognized stock-based compensation weighted average recognition period     2 years 9 months 18 days          
Unrecognized stock-based compensation     $ 43.9          
Maximum | Employees And Non Employees                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Share based compensation award expiration period     10 years          
Minimum                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Percentage of employees purchase price of common stock     100.00%          
Minimum | 10% Shareholder                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Percentage of employees purchase price of common stock     110.00%          
Minimum | Employees And Non Employees                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Share based compensation award expiration period     7 years          
Underwritten Public Offering | 2019 Warrants                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Warrants outstanding     2,888,526          
Underwritten Public Offering | Warrant                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Number of warrants issued         2,040,816   2,866,961 2,945,026
Number of securities called by each warrant               1
Warrants, exercise price               $ 0.0001
Warrants, term 7 years              
Maximum ownership Percentage 9.99%              
Underwritten Public Offering | Warrant | Maximum                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Maximum ownership Percentage 19.99%              
Underwritten Public Offering | Warrant | Minimum                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Prior notice period 61 days              
At The Market Offering | Maximum | Cowen                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Common stock aggregate offering price   $ 100.0            
Percentage of commission to be paid on gross sales proceeds of common stock sold   3.00%            
2020 ATM Facility | Cowen                
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                
Common stock, shares issued     1,319,878          
Common stock average price     $ 15.88          
Proceeds from sale of common stock, gross     $ 21.0          
Proceeds from sale of common stock, net     20.5          
Common stock value remaining to be sold     $ 57.4