STOCK-BASED COMPENSATION (Details 4) - USD ($)	12 Months Ended
	Dec. 31, 2018	Dec. 31, 2017
Stock-based compensation expense in operating expenses:
Total Stock-based Compensation Expense	$ 1,168,616	$ 874,386
Research and development [Member]
Stock-based compensation expense in operating expenses:
Total Stock-based Compensation Expense	727,216	608,456
General and administrative [Member]
Stock-based compensation expense in operating expenses:
Total Stock-based Compensation Expense	$ 441,400	$ 265,930