The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108 320 11,981 SH   SOLE   11,981 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104 240 4,806 SH   SOLE   4,806 0 0
ALEXION PHARMACEUTICALS INC COM 015351109 1,300 9,927 SH   SOLE   9,927 0 0
ALNYLAM PHARMACEUTICALS INC COM 02043Q107 969 13,351 SH   SOLE   13,351 0 0
AMARIN CORP PLC SPONS ADR NEW 023111206 323 16,641 SH   SOLE   16,641 0 0
AMGEN INC COM 031162100 257 1,397 SH   SOLE   1,397 0 0
AMICUS THERAPEUTICS INC COM 03152W109 458 36,731 SH   SOLE   36,731 0 0
ANAPTYSBIO INC COM 032724106 345 6,116 SH   SOLE   6,116 0 0
ARENA PHARMACEUTICALS INC COM NEW 040047607 573 9,770 SH   SOLE   9,770 0 0
ASCENDIS PHARMA A S SPONSORED ADR 04351P101 713 6,190 SH   SOLE   6,190 0 0
AUDENTES THERAPEUTICS INC COM 05070R104 656 17,339 SH   SOLE   17,339 0 0
BIO TECHNE CORP COM 09073M104 323 1,551 SH   SOLE   1,551 0 0
BIOGEN INC COM 09062X103 263 1,123 SH   SOLE   1,123 0 0
BIOHAVEN PHARMACTL HLDG CO L COM G11196105 475 10,852 SH   SOLE   10,852 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 805 9,400 SH   SOLE   9,400 0 0
BLUEBIRD BIO INC COM 09609G100 743 5,840 SH   SOLE   5,840 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109 640 6,780 SH   SOLE   6,780 0 0
BRISTOL MYERS SQUIBB CO COM 110122108 1,497 33,000 SH   SOLE   33,000 0 0
ISHARES TR NASDAQ BIOTECH 464287556 9,274 85,000 SH Call SOLE   85,000 0 0
CELGENE CORP COM 151020104 520 5,625 SH   SOLE   5,625 0 0
CHARLES RIV LABS INTL INC COM 159864107 300 2,112 SH   SOLE   2,112 0 0
CHECKPOINT THERAPEUTICS INC COM 162828107 342 112,760 SH   SOLE   112,760 0 0
CRISPR THERAPEUTICS AG NAMEN AKT H17182108 622 13,214 SH   SOLE   13,214 0 0
DECIPHERA PHARMACEUTICALS IN COM 24344T101 420 18,631 SH   SOLE   18,631 0 0
DIREXION SHS ETF TR SP BIOTCH BL NEW 25490K323 4,940 98,432 SH   SOLE   98,432 0 0
EPIZYME INC COM 29428V104 632 50,378 SH   SOLE   50,378 0 0
EXACT SCIENCES CORP COM 30063P105 1,007 8,534 SH   SOLE   8,534 0 0
EXELIXIS INC COM 30161Q104 244 11,440 SH   SOLE   11,440 0 0
FIBROGEN INC COM 31572Q808 221 4,883 SH   SOLE   4,883 0 0
FORTRESS BIOTECH INC COM 34960Q109 351 234,030 SH   SOLE   234,030 0 0
G1 THERAPEUTICS INC COM 3621LQ109 639 20,844 SH   SOLE   20,844 0 0
GILEAD SCIENCES INC COM 375558103 276 4,082 SH   SOLE   4,082 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 499 9,479 SH   SOLE   9,479 0 0
GRIFOLS S A SP ADR REP B NVT 398438408 278 13,196 SH   SOLE   13,196 0 0
GW PHARMACEUTICALS PLC ADS 36197T103 633 3,674 SH   SOLE   3,674 0 0
ILLUMINA INC COM 452327109 1,730 4,699 SH   SOLE   4,699 0 0
IMMUNOMEDICS INC COM 452907108 868 62,575 SH   SOLE   62,575 0 0
INCYTE CORP COM 45337C102 902 10,613 SH   SOLE   10,613 0 0
INSMED INC COM PAR $.01 457669307 690 26,936 SH   SOLE   26,936 0 0
INTELLIA THERAPEUTICS INC COM 45826J105 466 28,490 SH   SOLE   28,490 0 0
INTERCEPT PHARMACEUTICALS IN COM 45845P108 467 5,872 SH   SOLE   5,872 0 0
IONIS PHARMACEUTICALS INC COM 462222100 1,293 20,124 SH   SOLE   20,124 0 0
IQVIA HLDGS INC COM 46266C105 319 1,985 SH   SOLE   1,985 0 0
ISHARES TR NASDAQ BIOTECH 464287556 13,638 125,000 SH   SOLE   125,000 0 0
LIGAND PHARMACEUTICALS INC COM NEW 53220K504 241 2,111 SH   SOLE   2,111 0 0
MACROGENICS INC COM 556099109 510 30,075 SH   SOLE   30,075 0 0
MADRIGAL PHARMACEUTICALS INC COM 558868105 374 3,570 SH   SOLE   3,570 0 0
METTLER TOLEDO INTERNATIONAL COM 592688105 2,717 3,235 SH   SOLE   3,235 0 0
NEKTAR THERAPEUTICS COM 640268108 445 12,503 SH   SOLE   12,503 0 0
NEUROCRINE BIOSCIENCES INC COM 64125C109 254 3,012 SH   SOLE   3,012 0 0
PACIRA BIOSCIENCES COM 695127100 489 11,250 SH   SOLE   11,250 0 0
PROQR THRAPEUTICS N V SHS EURO N71542109 1,260 138,461 SH   SOLE   138,461 0 0
QIAGEN NV SHS NEW N72482123 1,170 28,858 SH   SOLE   28,858 0 0
RECRO PHARMA INC COM 75629F109 115 11,353 SH   SOLE   11,353 0 0
REGENERON PHARMACEUTICALS COM 75886F107 695 2,221 SH   SOLE   2,221 0 0
SAREPTA THERAPEUTICS INC COM 803607100 813 5,353 SH   SOLE   5,353 0 0
SEATTLE GENETICS INC COM 812578102 1,239 17,901 SH   SOLE   17,901 0 0
SPARK THERAPEUTICS INC COM 84652J103 993 9,699 SH   SOLE   9,699 0 0
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108 322 5,064 SH   SOLE   5,064 0 0
UNIQURE NV SHS N90064101 1,111 14,215 SH   SOLE   14,215 0 0
VERTEX PHARMACEUTICALS INC COM 92532F100 1,502 8,193 SH   SOLE   8,193 0 0
VIKING THERAPEUTICS INC COM 92686J106 402 48,485 SH   SOLE   48,485 0 0
ZOGENIX INC COM NEW 98978L204 465 9,725 SH   SOLE   9,725 0 0