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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE

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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
BLUEPRINT MEDICINES CORP COM 09627Y109 157,768 7,393,059 SH   DFND   7,393,059 0 0
ELEVEN BIOTHERAPEUTICS INC COM 286221106 11,668 4,841,591 SH   DFND   4,841,591 0 0
GLOBAL BLOOD THERAPEUTICS IN COM 37890U108 622,320 14,760,900 SH   DFND   14,760,900 0 0
SAGE THERAPEUTICS INC COM 78667J108 272,664 6,442,916 SH   DFND   6,442,916 0 0
ZAFGEN INC COM 98885E103 6,721 210,371 SH   DFND   210,371 0 0