Condensed Statements of Cash Flows - USD ($) $ in Thousands	6 Months Ended
	Jun. 30, 2024	Jun. 30, 2023
Cash flows from operating activities
Net loss	$ (139,648)	$ (99,419)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	1,328	920
Stock-based compensation expense	23,118	18,557
Amortization of premiums and discounts on marketable securities, net	(7,435)	(5,071)
Non-cash operating lease costs	1,652	1,420
Changes in operating assets and liabilities:
Prepaid and other assets	(12,112)	(5,642)
Accounts payable and accrued liabilities	6,047	(816)
Accrued compensation	(1,509)	(4,663)
Operating lease liabilities	(1,819)	(1,594)
Deferred revenue	(5,006)	(2,466)
Net cash used in operating activities	(135,384)	(98,774)
Cash flows from investing activities
Maturities of marketable securities	207,930	128,215
Purchases of marketable securities	(514,100)	(275,404)
Purchases of property and equipment	(1,446)	(2,442)
Net cash used in investing activities	(307,616)	(149,631)
Cash flows from financing activities
Proceeds from issuance of common stock in public offerings, net of issuance costs	438,902	60,547
Proceeds from issuance of common stock under employee incentive equity plans	17,484	1,386
Proceeds from the issuance of common stock in a private placement, net of issuance costs	238,388	0
Proceeds from issuance of pre-funded warrants in a private placement, net of issuance costs	141,395	0
Net cash provided by financing activities	836,169	61,933
Net increase (decrease) in cash, cash equivalents and restricted cash	393,169	(186,472)
Cash, cash equivalents and restricted cash at beginning of period	185,377	340,647
Cash, cash equivalents and restricted cash at end of period	578,546	154,175
Supplemental schedule of noncash investing and financing activities:
Costs incurred, but not paid, in connection with deferred financing costs included in accounts payable and accrued liabilities	536	0
Receivables from stock option exercises included in prepaid and other assets	$ 1,747	$ 0