Statements of Stockholders’ Equity - USD ($) shares in Thousands, $ in Thousands	Total	Private Placement	Public Stock Offering	Common Stock	Common Stock Private Placement	Common Stock Public Stock Offering	Additional Paid-in Capital	Additional Paid-in Capital Private Placement	Additional Paid-in Capital Public Stock Offering	Accumulated Other Comprehensive Income (Loss)	Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2020				37,569
Beginning balance at Dec. 31, 2020	$ 306,223			$ 4			$ 372,764			$ (5)	$ (66,540)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock, net of issuance costs (in shares)				9,980
Issuance of common stock, net of issuance costs	174,677			$ 1			174,676
Issuance of common stock upon exercise of stock options (in shares)				172
Issuance of common stock upon exercise of stock options	930						930
Issuance of common stock under employee stock purchase plan (in shares)				33
Issuance of common stock under employee stock purchase plan	709						709
Vesting of early exercise options	26						26
Stock-based compensation	17,056						17,056
Net loss	(118,009)										(118,009)
Other comprehensive loss (income)	(182)									(182)
Ending balance (in shares) at Dec. 31, 2021				47,754
Ending balance at Dec. 31, 2021	381,430			$ 5			566,161			(187)	(184,549)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock, net of issuance costs (in shares)				21,572
Issuance of common stock, net of issuance costs	344,616			$ 2			344,614
Issuance of common stock upon exercise of stock options (in shares)				351
Issuance of common stock upon exercise of stock options	470						470
Issuance of common stock under employee stock purchase plan (in shares)				91
Issuance of common stock under employee stock purchase plan	922						922
Vesting of early exercise options	4						4
Stock-based compensation	27,139						27,139
Net loss	(173,995)										(173,995)
Other comprehensive loss (income)	$ (2,511)									(2,511)
Ending balance (in shares) at Dec. 31, 2022	69,768			69,768
Ending balance at Dec. 31, 2022	$ 578,075			$ 7			939,310			(2,698)	(358,544)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock, net of issuance costs (in shares)					5,075	4,107
Issuance of common stock, net of issuance costs		$ 31,190	$ 60,547		$ 1			$ 31,189	$ 60,547
Issuance of common stock upon exercise of stock options (in shares)	149			149
Issuance of common stock upon exercise of stock options	$ 573						573
Issuance of common stock under employee stock purchase plan (in shares)				176
Issuance of common stock under employee stock purchase plan	1,554						1,554
Stock-based compensation	38,222						38,222
Net loss	(212,220)										(212,220)
Other comprehensive loss (income)	$ 2,823									2,823
Ending balance (in shares) at Dec. 31, 2023	79,275			79,275
Ending balance at Dec. 31, 2023	$ 500,764			$ 8			$ 1,071,395			$ 125	$ (570,764)