Condensed Statements of Stockholders' Equity (Unaudited) - USD ($) $ in Thousands	Total	Common Stock	Additional Paid-in Capital	Accumulated Other Comprehensive Loss	Accumulated Deficit
Beginning balance (in shares) at Dec. 31, 2021		47,754,000
Beginning balance at Dec. 31, 2021	$ 381,430	$ 5	$ 566,161	$ (187)	$ (184,549)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)		7,000
Issuance of common stock upon exercise of stock options	10		10
Issuance of common stock in public offerings, net of issuance costs (in shares)		1,520,000
Issuance of common stock in public offerings, net of issuance costs	24,103		24,103
Vesting of early exercise options	1		1
Stock-based compensation	6,238		6,238
Net loss	(34,235)				(34,235)
Other comprehensive income (loss)	(1,839)			(1,839)
Ending balance (in shares) at Mar. 31, 2022		49,281,000
Ending balance at Mar. 31, 2022	375,708	$ 5	596,513	(2,026)	(218,784)
Beginning balance (in shares) at Dec. 31, 2021		47,754,000
Beginning balance at Dec. 31, 2021	381,430	$ 5	566,161	(187)	(184,549)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Net loss	(123,524)
Ending balance (in shares) at Sep. 30, 2022		54,446,000
Ending balance at Sep. 30, 2022	376,982	$ 5	688,513	(3,463)	(308,073)
Beginning balance (in shares) at Mar. 31, 2022		49,281,000
Beginning balance at Mar. 31, 2022	375,708	$ 5	596,513	(2,026)	(218,784)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)		5,000
Issuance of common stock upon exercise of stock options	4		4
Issuance of common stock in public offerings, net of issuance costs (in shares)		2,746,000
Issuance of common stock in public offerings, net of issuance costs	38,281		38,281
Vesting of early exercise options	1		1
Issuance of common stock under Employee Stock Purchase Plan (in shares)		49,000
Issuance of common stock under Employee Stock Purchase Plan	499		499
Stock-based compensation	6,508		6,508
Net loss	(45,690)				(45,690)
Other comprehensive income (loss)	(960)			(960)
Ending balance (in shares) at Jun. 30, 2022		52,081,000
Ending balance at Jun. 30, 2022	374,351	$ 5	641,806	(2,986)	(264,474)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)		270,000
Issuance of common stock upon exercise of stock options	303		303
Issuance of common stock in public offerings, net of issuance costs (in shares)		2,095,000
Issuance of common stock in public offerings, net of issuance costs	39,317		39,317
Vesting of early exercise options	1		1
Stock-based compensation	7,086		7,086
Net loss	(43,599)				(43,599)
Other comprehensive income (loss)	(477)			(477)
Ending balance (in shares) at Sep. 30, 2022		54,446,000
Ending balance at Sep. 30, 2022	$ 376,982	$ 5	688,513	(3,463)	(308,073)
Beginning balance (in shares) at Dec. 31, 2022	69,768,000	69,768,000
Beginning balance at Dec. 31, 2022	$ 578,075	$ 7	939,310	(2,698)	(358,544)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)		102,000
Issuance of common stock upon exercise of stock options	520		520
Issuance of common stock in public offerings, net of issuance costs (in shares)		943,000
Issuance of common stock in public offerings, net of issuance costs	22,441		22,441
Stock-based compensation	9,104		9,104
Net loss	(52,394)				(52,394)
Other comprehensive income (loss)	1,169			1,169
Ending balance (in shares) at Mar. 31, 2023		70,813,000
Ending balance at Mar. 31, 2023	$ 558,915	$ 7	971,375	(1,529)	(410,938)
Beginning balance (in shares) at Dec. 31, 2022	69,768,000	69,768,000
Beginning balance at Dec. 31, 2022	$ 578,075	$ 7	939,310	(2,698)	(358,544)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)	145,000
Net loss	$ (151,777)
Ending balance (in shares) at Sep. 30, 2023	74,101,000	74,101,000
Ending balance at Sep. 30, 2023	$ 517,468	$ 7	1,029,660	(1,878)	(510,321)
Beginning balance (in shares) at Mar. 31, 2023		70,813,000
Beginning balance at Mar. 31, 2023	558,915	$ 7	971,375	(1,529)	(410,938)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)		12,000
Issuance of common stock upon exercise of stock options	7		7
Issuance of common stock in public offerings, net of issuance costs (in shares)		3,164,000
Issuance of common stock in public offerings, net of issuance costs	38,106		38,106
Issuance of common stock under Employee Stock Purchase Plan (in shares)		81,000
Issuance of common stock under Employee Stock Purchase Plan	859		859
Stock-based compensation	9,453		9,453
Net loss	(47,025)				(47,025)
Other comprehensive income (loss)	(1,137)			(1,137)
Ending balance (in shares) at Jun. 30, 2023		74,070,000
Ending balance at Jun. 30, 2023	559,178	$ 7	1,019,800	(2,666)	(457,963)
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock upon exercise of stock options (in shares)		31,000
Issuance of common stock upon exercise of stock options	40		40
Stock-based compensation	9,820		9,820
Net loss	(52,358)				(52,358)
Other comprehensive income (loss)	$ 788			788
Ending balance (in shares) at Sep. 30, 2023	74,101,000	74,101,000
Ending balance at Sep. 30, 2023	$ 517,468	$ 7	$ 1,029,660	$ (1,878)	$ (510,321)