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Insider Trading Arrangements
 3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2023
Trading Arrangements, by Individual    
Material Terms of Trading Arrangement   From time to time, our officers (as defined in Rule 16a–1(f)) and directors may enter into Rule 10b5-1 or non-Rule 10b5-1 trading arrangements (as each such term is defined in Item 408 of Regulation S-K). During the
three months ended September 30, 2023, our officers and directors took the following actions with respect to 10b5-1 trading arrangements:
ActionDateTrading ArrangementTotal Shares to be SoldExpiration Date
Rule 10b5-1Non-Rule 10b5-1
Sarah Boyce (President, Chief Executive Officer and Director)
Adopt9/26/2023X(1)
(2)
Michael MacLean (Chief Financial and Chief Business Officer)
Adopt9/27/2023X(1)
(2)
Michael Flanagan (Chief Scientific and Technical Officer)
Adopt
9/26/2023
X
(1)
(2)
Teresa McCarthy (Chief Human Resources Officer)
Adopt
9/26/2023
X
(1)
(2)
Arthur Levin, Ph.D.(Distinguished Scientist and Strategic Leader; Director)
Adopt9/27/2023X(1)
(2)
____________________
(1)Under our 2020 Incentive Award Plan, recipients of RSUs and PSUs are required to sell a number of shares that satisfies applicable tax withholding obligations upon a taxable event such as a vesting date. Each participant listed in this table has executed an instruction letter to our broker for the sale of such minimum number of shares, at the then-applicable market price, sufficient to cover applicable tax withholding obligations, at the statutory minimum applicable statutory rate, for each such person. These instruction letters qualify as Rule 10b5-1 trading arrangements but may exist concurrent with another 10b5-1 trading arrangement for the same individual, as permitted by Rule 10b5-1(c)(1)(ii)(D)(3) under the Exchange Act.
(2)These instruction letters shall remain in effect for so long as the individual owns RSUs or PSUs.
Non-Rule 10b5-1 Arrangement Adopted false  
Rule 10b5-1 Arrangement Terminated false  
Non-Rule 10b5-1 Arrangement Terminated false  
Sarah Boyce [Member]    
Trading Arrangements, by Individual    
Name Sarah Boyce  
Title (President, Chief Executive Officer and Director)  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 9/26/2023  
Michael MacLean [Member]    
Trading Arrangements, by Individual    
Name Michael MacLean  
Title (Chief Financial and Chief Business Officer)  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 9/27/2023  
Michael Flanagan [Member]    
Trading Arrangements, by Individual    
Name Michael Flanagan  
Title (Chief Scientific and Technical Officer)  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 9/26/2023  
Teresa McCarthy [Member]    
Trading Arrangements, by Individual    
Name Teresa McCarthy  
Title (Chief Human Resources Officer)  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 9/26/2023  
Arthur Levin, Ph.D. [Member]    
Trading Arrangements, by Individual    
Name Arthur Levin, Ph.D.  
Title (Distinguished Scientist and Strategic Leader; Director)  
Rule 10b5-1 Arrangement Adopted true  
Adoption Date 9/27/2023