Collaboration, License and Research Agreements - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended		27 Months Ended
	Mar. 31, 2023	Mar. 31, 2022	Mar. 31, 2023	Dec. 31, 2022
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized	$ 2,233	$ 1,795
Research Collaboration and License Agreement with Eli Lilly
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Revenue recognized	2,200	$ 1,700
Collaboration receivables	$ 1,000		$ 1,000	$ 2,100
Research Collaboration with MyoKardia, Inc.
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Aggregate funding received from collaboration and research service agreements			$ 40,200