Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended			30 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2022
Cash flows from operating activities
Net loss	$ (173,995)	$ (118,009)	$ (44,355)
Adjustments to reconcile net loss to net cash used in operating activities:
Depreciation	1,387	639	373
Stock-based compensation expense	27,139	17,056	4,310
Amortization of premiums and discounts on marketable securities, net	(615)	179	9
Other non-cash adjustments	0	(16)	214
Changes in operating assets and liabilities:
Prepaid and other assets	(6,616)	(2,510)	(2,444)
Accounts payable and accrued liabilities	18,315	6,043	5,749
Accrued compensation	2,250	5,788	1,838
Operating lease right-of-use assets and liabilities, net	987	461	289
Deferred revenue	(5,120)	(4,444)	(3,100)
Net cash used in operating activities	(136,268)	(94,813)	(37,117)
Cash flows from investing activities
Purchases of marketable securities	(355,837)	(85,357)	(6,693)
Maturities of marketable securities	168,705	6,580	0
Purchases of property and equipment	(2,823)	(3,740)	(1,092)
Net cash used in investing activities	(189,955)	(82,517)	(7,785)
Cash flows from financing activities
Net proceeds from Issuance of common stock after deducting offering-related transaction costs and commissions	344,779	174,677	274,054	$ 519,300
Proceeds from the issuance of common stock under employee incentive equity plans	1,392	1,639	466
Payments on long-term debt	0	0	(4,683)
Proceeds from issuance of Series C convertible preferred stock, net of issuance costs	0	0	2,200
Net cash provided by financing activities	346,171	176,316	272,037
Net (decrease) increase in cash, cash equivalents and restricted cash	19,948	(1,014)	227,135
Cash, cash equivalents and restricted cash at beginning of period	320,699	321,713	94,578
Cash, cash equivalents and restricted cash at end of period	340,647	320,699	321,713	$ 340,647
Supplemental disclosure of cash flow information:
Cash paid for interest	0	0	571
Supplemental schedule of noncash investing and financing activities:
Right-of-use assets obtained in exchange for operating lease liabilities	0	12,074	936
Costs incurred, but not paid, in connection with public offering included in accounts payable and accrued liabilities	163	0	0
Costs incurred, but not paid, in connection with purchases of property and equipment included in accounts payable and accrued liabilities	233	220	118
Conversion of convertible preferred stock into common stock upon completion of initial public offering	$ 0	$ 0	$ 136,920