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Stockholders' Equity - Additional Information (Details) - USD ($)
$ / shares in Units, $ in Thousands
1 Months Ended 12 Months Ended 30 Months Ended
Dec. 15, 2022
Nov. 08, 2022
Aug. 06, 2021
Jul. 02, 2021
Jun. 16, 2020
Dec. 31, 2022
Jun. 30, 2020
Jan. 31, 2020
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Dec. 31, 2022
Dec. 31, 2022
Dec. 31, 2019
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Common stock shares authorized (in shares)         400,000,000 400,000,000     400,000,000 400,000,000   400,000,000 400,000,000  
Preferred stock undesignated shares authorized (in shares)         40,000,000                  
Common stock par value per share (in dollars per share)         $ 0.0001 $ 0.0001     $ 0.0001 $ 0.0001   $ 0.0001 $ 0.0001  
Preferred stock par value per share (in dollars per share)         $ 0.0001                  
Preferred stock, shares outstanding (in shares)           0     0 0 0 0 0  
Public offering issuance costs                 $ 18,230 $ 11,262 $ 24,026      
Net proceeds from Issuance of common stock after deducting offering-related transaction costs and commissions                 $ 344,779 $ 174,677 $ 274,054   $ 519,300  
Preferred stock, shares issued (in shares)                           37,267,331
Issuance of Series C convertible preferred stock, net of issuance costs (in shares)               537,232     538,000      
Shares reserved for future issuance (in shares)           2,537,000     2,537,000 2,575,000   2,537,000 2,537,000  
Award vesting period                 4 years          
Expected dividend yield                 0.00%          
Employee Stock                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Shares reserved for future issuance (in shares)           548,028     548,028     548,028 548,028  
Participant maximum contribution as percentage of eligible compensation             15.00%              
Award offering period                 6 months          
Percentage of purchase price of shares of lower of fair market value             85.00%              
Shares issued under ESPP (in shares)                 90,535 33,147 28,979      
Expected term (in years)                 6 months 6 months 6 months      
Expected dividend yield                 0.00% 0.00% 0.00%      
Unrecognized compensation cost           $ 400     $ 400     $ 400 $ 400  
Weighted-average period of unrecognized compensation cost                 6 months          
Stock Options                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Expected dividend yield                 0.00% 0.00% 0.00%      
Unrecognized compensation cost           65,100     $ 65,100     65,100 65,100  
Weighted-average period of unrecognized compensation cost                 2 years 7 months 6 days          
Accounts Payable and Accrued Liabilities | Employee Stock                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Outstanding liability           $ 78     $ 78     $ 78 $ 78  
Maximum | Stock Options                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Expected term (in years)                 6 years 1 month 6 days 6 years 1 month 6 days 6 years 1 month 6 days      
Minimum | Stock Options                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Expected term (in years)                 5 years 6 months 5 years 6 months 5 years 4 months 24 days      
2013 Equity Incentive Plan | Maximum                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Expiration period                 10 years          
2020 Incentive Award Plan                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Shares reserved for future issuance (in shares)             3,900,000              
Percentage of shares of common stock outstanding on final day of immediately preceding calendar year             5.00%              
Additional shares reserved for future issuance (in shares)                 2,387,000     4,266,161    
2020 Incentive Award Plan | Maximum                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Expiration period                 10 years          
2022 Employment Inducement Incentive Award Plan                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Additional shares reserved for future issuance (in shares)           1,500,000     1,500,000          
2022 Employment Inducement Incentive Award Plan | Maximum                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Expiration period                 10 years          
Common Stock                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Outstanding shares of convertible preferred stock converted into common stock (in shares)                     17,921,000      
Shares issued under ESPP (in shares)                 91,000 33,000 29,000      
Public Offering                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Sale of stock number of shares issued in transaction (in shares)         16,560,000                  
Sale of stock, price per share (in dollars per share)         $ 18.00                  
Public offering issuance costs         $ 24,000                  
Proceeds from the IPO, net of underwriting discounts, commissions and offering costs         $ 274,100                  
Outstanding shares of convertible preferred stock converted into common stock (in shares)         17,921,069                  
Public Offering | Common Stock                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Common stock shares authorized (in shares)         400,000,000                  
Outstanding shares of convertible preferred stock converted into common stock (in shares)             17,921,069              
Private Placement, 2021 Sales Agreement | Sales Agent                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Sale of stock number of shares issued in transaction (in shares)                 7,771,812,000 780,549        
Public offering issuance costs                 $ 3,700 $ 700        
Sale of common stock maximum aggregate offering price       $ 150,000                    
Net proceeds from Issuance of common stock after deducting offering-related transaction costs and commissions                 $ 121,100 $ 19,600        
Private Placement, 2022 Sales Agreement | Sales Agent                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Sale of common stock maximum aggregate offering price   $ 200,000                        
Follow-on Public Offering | Common Stock                            
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]                            
Sale of stock number of shares issued in transaction (in shares) 13,800,000   9,200,000                      
Sale of stock, price per share (in dollars per share) $ 17.25   $ 18.00                      
Public offering issuance costs $ 14,300   $ 10,500                      
Proceeds from the follow-on public offering, net of underwriting discounts, commissions and offering costs $ 223,800   $ 155,100